Regulation of Development, Differentiation and Gene Expression in Health and Disease
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Predictive Potential of Angiogenic Growth Factors and Circulating Endothelial Cells in Breast Cancer Patients Receiving Metronomic Chemotherapy Plus Bevacizumab
2009
Yuval Shaked, PhDAuthors : Calleri A, Bono A, Bagnardi V, Quarna J, Mancuso P, Rabascio C, Dellapasqua S, Campagnoli E, Shaked Y, Goldhirsch A, Colleoni M, Bertolini F.
Clin Cancer Res. 2009 Dec 15;15(24):7652-7657
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A novel human heparanase splice variant, T5, endowed with rotumorigenic characteristics
2009
Israel Vlodavsky, PhDAuthors : Barash U, Cohen-Kaplan V, Arvatz G, Gingis-Velitski S, Levy-Adam F, Nativ O, Shemesh R, Ayalon-Sofer M, Ilan N, Vlodavsky I.
FASEB J. . [Epub ahead of print]
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The proprioceptive and contractile systems in Drosophila are both patterned by the EGR family transcription factor Stripe
2009
Adi Salzberg, DScAuthors : Klein, Y., Halachmi, N., Egoz-Matia,N., Toder, M., and Salzberg, A.
Dev Biol. 2009, Available online 24 November.
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Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development
2009
Dale Frank, PhDAuthors : Gutkovich Y, Ofir R, Elkouby YM, Dibner C, Gefen A, Elias S, Frank D.
Dev Biol. 2009 Nov 24.
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A Novel JNK Binding Protein WDR62 Is Recruited to Stress Granules and Mediates a Non-classical JNK Activation
2009
Ami Aronheim, PhDAuthors : Wasserman T, Katsenelson K, Daniliuc S, Hasin T, Choder M, Aronheim A.
Mol Biol Cell. 2009 Nov 12.
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A simple technique for the placement of Schanz screws into bone using minimal radiologic control
2009
Trop Doct. 2009 Oct 22. [Epub ahead of print]
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Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents
2009
Yuval Shaked, PhDAuthors : Shaked Y, Tang T, Woloszynek J, Daenen LG, Man S, Xu P, Cai SR, Arbeit JM, Voest EE, Chaplin DJ, Smythe J, Harris A, Nathan P, Judson I, Rustin G, Bertolini F, Link DC, Kerbel RS.
Cancer Res. 2009 69:7524-8.
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Heparanase: busy at the cell surface
2009
Trends Biochem Sci. 2009 34, 511-9.
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Neural ectoderm-secreted FGF initiates the expression of Nkx2.5 in cardiac progenitors via a p38 MAPK/CREB pathway
2009
Dev Biol. 2009 Sep 15. [Epub ahead of print]
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Heparanase expression by Barrett's epithelium and during esophageal carcinoma progression
2009
Israel Vlodavsky, PhDAuthors : Brun R, Naroditsky I, Waterman M, Ben-Izhak O, Groisman G, Ilan N, Vlodavsky I.
Mod Pathol. 2009 Sep 11. [Epub ahead of print]
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Bone marrow derived cells in tumor angiogenesis and growth: are they the good, the bad or the evil?
2009
Biochim Biophys Acta. 2009 1796(1):1-4.
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Patients aged 80 and older undergoing orthopedic or urologic surgery: a prospective study focusing on perioperative morbidity and mortality
2009
Michael Soudry, MDAuthors : Peled E, Keren Y, Halachmi S, Soudry M, Zinman C, Kats Y, Barak M.
Gerontology. 2009;55(5):517-22
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Transplanted blood-derived endothelial progenitor cells (EPC) enhance bridging of sheep tibia critical size defects
2009
Michael Soudry, MDAuthors : Rozen N, Bick T, Bajayo A, Shamian B, Schrift-Tzadok M, Gabet Y, Yayon A, Bab I, Soudry M, Lewinson D.
Bone. 2009 Aug 6.
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DamID: A Methylation-Based Chromatin Profiling Approach
2009
Methods Mol Biol. 2009;567:155-69.
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Reactive nitrogen species induce nuclear factor-kappaB-mediated protein degradation in skeletal muscle cells
2009
Free Radic Biol Med 40, 2112-2125.
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Long-term results after Ilizarov treatment for severe high-energy injuries of the elbow
2009
J Trauma. 2009 Jun;66(6):1647-52.
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Plasma heparanase as a significant marker of treatment response in children with Hodgkin lymphoma: pilot study
2009
Pediatr Hematol Oncol. 2009 Jun;26(4):157-64.
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Nicotine modulates bone metabolism-associated gene expression in osteoblast cells
2009
J Bone Miner Metab. 2009;27(5):555-61
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Marasmius oreades substances block NF-kappaB activity through interference with IKK activation pathway
2009
Abraham Z. Reznick, PhDAuthors : Petrova RD, Mahajna J, Wasser SP, Ruimi N, Denchev CM, Sussan S, Nevo E, Reznick AZ.
Mol Biol Rep. 2009 Apr;36(4):737-44.
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The ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of its homologue immediate early gene counterpart, ATF3
2009
Ami Aronheim, PhDAuthors : Weidenfeld-Baranboim K, Hasin T, Darlyuk I, Heinrich R, Elhanani O, Pan J, Yokoyama KK, Aronheim A.
Nucleic Acids Res. 2009 Apr;37(7):2194-203.
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The Expression and Prognostic Significance of Cks1 in Salivary Cancer
2009
Dan Hershko, MDAuthors : Nagler RM, Ben-Izhak O, Ostrovsky D, Golz A, Hershko DD.
Cancer Invest. 2009 Mar 23:1. [Epub ahead of print]
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Structure-function approach identifies a COOH-terminal domain that mediates heparanase signaling
2009
Israel Vlodavsky, PhDAuthors : Fux L, Feibish N, Cohen-Kaplan V, Gingis-Velitski S, Feld S, Geffen C, Vlodavsky I, Ilan N.
Cancer Res. 2009 Mar 1;69(5):1758-67. Epub 2009 Feb 24.
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Alternatively spliced Spalax heparanase inhibits extracellular matrix degradation, tumor growth, and metastasis
2009
Israel Vlodavsky, PhDAuthors : Nasser NJ, Avivi A, Shafat I, Edovitsky E, Zcharia E, Ilan N, Vlodavsky I, Nevo E.
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2253-8.
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The evolutionary theories of aging revisited -a mini-review
2009
Gerontology. 2009;55(2):205-16. Epub 2009 Feb 7
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A p38 MAPK-CREB pathway functions to pattern mesoderm in Xenopus
2008
Dev Biol. 2008 Oct 1;322(1):86-94. Epub 2008 Jul 16
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Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells
2008
PLoS ONE. 2008 Sep 26;3(9):e3287
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Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents
2008
Yuval Shaked, PhDAuthors : Shaked, Y., Henke, E., Roodhart, J. M. L., Mancuso, P., Langenberg, M. H. G., Colleoni, M., Daenen, L. G., Man, S., Xu, P., Emmenegger, U., Tang, T., Zhu, Z., Witte, L., Streiter, R. M., Bertolini, F., Voest, E. E., Benezra, R., Kerbel, R. S.
Cancer Cell 14, 263-273.
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Heparanase is overexpressed in lung cancer and correlates inversely with patient survival
2008
Israel Vlodavsky, PhDAuthors : Cohen E, Doweck I, Naroditsky I, Ben-Izhak O, Kremer R, Best LA, Vlodavsky I, Ilan N.
Cancer. 2008 Sep 1;113(5):1004-11
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Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases
2008
Gera Neufeld, PhDAuthors : Varshavsky A, Kessler O, Abramovitch S, Kigel B, Zaffryar S, Akiri G, Neufeld G.
Cancer Res. 2008 Sep 1;68(17):6922-31
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Inhibition of myoblast differentiation by tumor necrosis factor alpha is mediated by c-Jun N-terminal kinase 1 and leukemia inhibitory factor
2008
J Biol Chem. 2008 Aug 22;283(34):23224-34. Epub 2008 Jun 15
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Heparanase: one molecule with multiple functions in cancer progression
2008
Israel Vlodavsky, PhDAuthors : Vlodavsky I, Elkin M, Abboud-Jarrous G, Levi-Adam F, Fuks L, Shafat I, Ilan N.
Connect Tissue Res. 2008;49(3):207-10.
PMID: 18661344
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Overexpression of Skp2 is associated with resistance to preoperative doxorubicin - based chemotherapy in primary breast cancer
2008
Dan Hershko, MDAuthors : Davidovich S, Ben-Izhak O, Shapira M, Futerman B, Hershko DD.
Breast Cancer Res. 2008 Jul 21;10(4):R63 [Epub ahead of print]
PMID: 18644126
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TRE-dependent transcription activation by JDP2-CHOP10 association
2008
Nucleic Acids Res. 2008 Jun;36(11):3608-19. Epub 2008 May 7.
PMID: 18463134
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The semaphorins: versatile regulators of tumour progression and tumour angiogenesis
2008
Nat Rev Cancer. 2008 Aug;8(8):632-45. Epub 2008 Jun 26. Review
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Transcription in the nucleus and mRNA decay in the cytoplasm are coupled processes
2008
Genes Dev. 2008 Aug 1;22(15):2022-7
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Chromosomal binding sites of the homeotic cofactor Homothorax
2008
Mol Genet Genomics. 2008 Jul;280(1):73-81. Epub 2008 May 15
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Left-sided perforated acute appendicitis in an adult with midgut malrotation: the role of computed tomography
2008
Dan Hershko, MDAuthors : Israelit S, Brook OR, Nira BR, Guralnik L, Hershko D.
Emerg Radiol. 2008 Jul 19. [Epub ahead of print]
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Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer.
2008
Cancer. 2008 Apr 1;112(7):1415-24. Review.
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Exercise and immobilization in aging animals: The involvement of oxidative stress and NF-kB activation
2008
Free Radic Biol Med 44, 202-214.
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Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells.
2008
Israel Vlodavsky, PhDAuthors : Nadir Y, Brenner B, Gingis-Velitski S, Levy-Adam F, Ilan N, Zcharia E, Nadir E
Thromb Haemost. 2008 Jan;99(1):133-41.
PMID: 18217145
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Differential effects of doxorubicin treatment on cell cycle arrest and Skp2 expression in breast cancer cells.
2007
Anticancer Drugs. 2007 Nov;18(10):1113-21.
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Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes.
2007
J Electrocardiol. 2007 Nov-Dec;40(6 Suppl):S192-6.
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Fracture repair: Modulation of fracture-callus and mechanical properties by sequential application of IL-6 following PTH 1-34 or PTH 28-48
2007
Michael Soudry, MDAuthors : Rozen, N., Lewinson, D., Bick, T., Jacob, C. Z., Soudry, M.
Bone 41, 437-445.
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Regulation of the cell cycle inhibitor p27 and its ubiquitin ligase Skp2 in differentiation of human embryonic stem cells.
2007
Dan Hershko, MDAuthors : Egozi D, Shapira M, Paor G, Ben-Izhak O, Skorecki K
FASEB J. 2007 Sep;21(11):2807-17.
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Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis.
2007
Gera Neufeld, PhDAuthors : Guttmann-Raviv N, Shraga-Heled N, Varshavsky A, Guimaraes-Sternberg C, Kessler O.
. J Biol Chem. 2007 Sep 7;282(36):26294-305.
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Additional sex combs affects antennal development by means of spatially restricted repression of Antp and Wg.
2007
Dev Dyn. 2007 Aug;236(8):2118-30.
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Antiangiogenic strategies on defense: on the possibility of blocking rebounds by the tumor vasculature after chemotherapy
2007
Cancer Res 67, 7055-7058.
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Role of bone regeneration and turnover modulators in control of fracture
2007
Michael Soudry, MDAuthors : Rozen, N., Lewinson, D., Bick, T., Meretyk, S., Soudry, M.
Crit Rev Eukaryot Gene Expr 17, 197-213.
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Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.
2007
Biochem J. 2007 Jun 15;404(3):487-97
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Safety of elective hand surgery following axillary lymph node dissection for breast cancer.
2007
Breast J. 2007 May-Jun;13(3):287-90.
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Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint.
2007
Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4870-5.
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Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor.
2007
FASEB J. 2007 Mar;21(3):915-26.
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Conceptual modeling of biological systems: the mRNA lifecycle as a case in point
2007
PLoS One, 2, e872
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Healing of critical-sized bone defects by endothelial progenitor cells
2007
Michael Soudry, MDAuthors : Lewinson, D., Rozen, N., Bick, T., Yayon, A., Shemian, B., Soudry, M.
J Bone Miner Res 22, s234.
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Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate.
2007
Curr Pharm Des. 2007;13(20):2057-73.
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Semaphorin signaling in vascular and tumor biology.
2007
Adv Exp Med Biol. 2007;600:118-31. Review.
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The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms.
2007
J. Cell Biol. 178, 1133-1143.
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Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart
2006
Tom Schultheiss, MD, PhDAuthors : Wu, S. M., Fujiwara, Y., Cibulsky, S. M., Clapham, D. E., Lien, C., Schultheiss, T. M., Orkin, S. H.
Cell 127, 1137-1150.
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Heparanase localization and expression by head and neck cancer: correlation with tumor progression and patient survival.
2006
Neoplasia. 2006 Dec;8(12):1055-61.
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Nucleocytoplasmic shuttling of the Rpb4p and Rpb7p subunits of Saccharomyces cerevisiae RNA polymerase II by two pathways.
2006
Eukaryot Cell. 2006 Dec;5(12):2092-103
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Expression of the ubiquitin ligase subunit cyclin kinase subunit 1 and its relationship to S-phase kinase protein 2 and p27Kip1 in prostate cancer.
2006
Dan Hershko, MDAuthors : Shapira M, Ben-Izhak O, Slotky M, Goldin O, Lahav-Baratz S, Hershko DD.
J Urol. 2006 Nov;176(5):2285-9.
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Heparanase induces tissue factor expression in vascular endothelial and cancer cells.
2006
Israel Vlodavsky, PhDAuthors : Nadir Y, Brenner B, Zetser A, Ilan N, Shafat I, Zcharia E, Goldshmidt O, Vlodavsky I.
J. Thromb Haemost. 2006 Nov;4(11):2443-51. Epub 2006 Sep
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Sources, derivation, and culture of human embryonic stem cells.
2006
Semin Reprod Med. 2006 Nov;24(5):298-303.
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A deleterious mutation in SAMD9 causes normophosphatemic familial tumoral calcinosis.
2006
Mordechai (Motti) Choder, PhDAuthors : Topaz O, Indelman M, Chefetz I, Geiger D, Metzker A, Altschuler Y, Choder M, Bercovich D, Uitto J, Bergman R, Richard G, Sprecher E.
Am J Hum Genet. 2006 Oct;79(4):759-64.
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The role of basic leucine zipper protein-mediated transcription in physiological and pathological myocardial hypertrophy.
2006
Ann N Y Acad Sci. 2006 Oct;1080:97-109.
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Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
2006
Yuval Shaked, PhDAuthors : Shaked, Y., Ciarrocchi, A., Franco, M., Lee, C. R., Man, S., Cheung, A. M., Hicklin, D. J., Chaplin, D., Foster, F. S., Benezra, R., Kerbel, R. S.
Science 313, 1785-1787.
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Prognostic role of p27Kip1 deregulation in colorectal cancer.
2006
Cancer. 2006 Aug 15;107(4):668-75. Review.
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Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells
2006
Tom Schultheiss, MD, PhDAuthors : James, R. G., Kamei, C. N., Wang, Q., Jiang, R., Schultheiss, T. M.
Development 133, 2995-3004.
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The mTOR inhibitor rapamycin downregulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells.
2006
Dan Hershko, MDAuthors : Shapira M, Kakiashvili E, Rosenberg T, Hershko DD.
Breast Cancer Res. 2006 Jul 19;8(4):R46 [Epub ahead of print]
PMID: 16859513
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Tumor suppressor p53 regulates heparanase gene expression.
2006
Oncogene. 2006 Jun 29;25(28):3939-47
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Is mechanical bowel preparation mandatory for left-sided colonic anastomosis? Results of a prospective randomized trial.
2006
Dan Hershko, MDAuthors : Zmora O, Mahajna A, Bar-Zakai B, Hershko D, Shabtai M, Krausz MM, Ayalon A.
Tech Coloproctol. 2006 Jun 19; [Epub ahead of print]
PMID: 16773286
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Halofuginone inhibits NF-{kappa}B and p38 MAPK in activated T cells.
2006
Israel Vlodavsky, PhDAuthors : Leiba M, Cahalon L, Shimoni A, Lider O, Zanin-Zhorov A, Hecht I, Sela U, Vlodavsky I, Nagler A.
J Leukoc Biol. 2006 Jun 12; [Epub ahead of print]
PMID: 16769768
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Generation and characterization of functional cardiomyocytes from rhesus monkey embryonic stem cells.
2006
Joseph Itskovitz-Eldor, MD, DScAuthors : Schwanke K, Wunderlich S, Reppel M, Winkler ME, Matzkies M, Groos S, Itskovitz-Eldor J, Simon AR, Hescheler J, Haverich A, Martin U.
Stem Cells. 2006 Jun;24(6):1423-32. Epub 2006 Mar 16.
PMID: 16543489
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Heparanase is expressed in osteoblastic cells and stimulates bone formation and bone mass.
2006
Israel Vlodavsky, PhDAuthors : Kram V, Zcharia E, Yacoby-Zeevi O, Metzger S, Chajek-Shaul T, Gabet Y, Muller R, Vlodavsky I, Bab I.
J Cell Physiol. 2006 Jun;207(3):784-92.
PMID: 16514606
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Heparin-like synthetic polymers, named RGTAs, mimic biological effects of heparin in vitro.
2006
Israel Vlodavsky, PhDAuthors : Rouet V, Meddahi-Pelle A, Miao HQ, Vlodavsky I, Caruelle JP, Barritault D.
J Biomed Mater Res A. 2006 Jun 1; [Epub ahead of print]
PMID: 16741978
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Inhibition of basic leucine zipper transcription is a major mediator of atrial dilatation.
2006
Ami Aronheim, PhDAuthors : Kehat I, Heinrich R, Ben-Izhak O, Miyazaki H, Gutkind JS, Aronheim A.
Cardiovasc Res. 2006 Jun 1;70(3):543-54. Epub 2006 Mar 6.
PMID: 16631626
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Spatial and temporal heparanase expression in colon mucosa throughout the adenoma-carcinoma sequence.
2006
Israel Vlodavsky, PhDAuthors : Doviner V, Maly B, Kaplan V, Gingis-Velitski S, Ilan N, Vlodavsky I, Sherman Y.
Mod Pathol. 2006 Jun;19(6):878-88.
PMID: 16607375
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Translocation of active heparanase to cell surface regulates degradation of extracellular matrix heparan sulfate upon transmigration of mature monocyte-derived dendritic cells.
2006
Israel Vlodavsky, PhDAuthors : Benhamron S, Nechushtan H, Verbovetski I, Krispin A, Abboud-Jarrous G, Zcharia E, Edovitsky E, Nahari E, Peretz T, Vlodavsky I, Mevorach D.
J Immunol. 2006 Jun 1;176(11):6417-24.
PMID: 16709798
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Role of endothelial heparanase in delayed-type hypersensitivity.
2006
Blood. 2006 May 1;107(9):3609-16. Epub 2005 Dec 29.
PMID: 16384929
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The "Sentinel Chain": a new concept for prediction of axillary node status in breast cancer patients.
2006
Dan Hershko, MDAuthors : Carmon M, Olsha O, Schecter WP, Raveh D, Reinus C, Hershko DD, Beller U, Golomb E.
Breast Cancer Res Treat. 2006 Apr 27; [Epub ahead of print]
PMID: 16642272
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The p38 MAPK signaling pathway: A major regulator of skeletal muscle development.
2006
Mol Cell Endocrinol. 2006 Apr 24; [Epub ahead of print]
PMID: 16644098
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Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cells survival and migration.
2006
Gera Neufeld, PhDAuthors : Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, Mandron M, Herault JP, Neufeld G, Savi P, Herbert JM, Bono F.
Blood. 2006 Apr 18; [Epub ahead of print]
PMID: 16621967
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Chromatin profiling, DamID and the emerging landscape of gene expression.
2006
Curr Opin Genet Dev. 2006 Apr;16(2):157-64. Epub 2006 Feb 28. Review.
PMID: 16503134
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Heparanase promotes growth, angiogenesis and survival of primary breast tumors.
2006
Israel Vlodavsky, PhDAuthors : Cohen I, Pappo O, Elkin M, San T, Bar-Shavit R, Hazan R, Peretz T, Vlodavsky I, Abramovitch R.
Int J Cancer. 2006 Apr 1;118(7):1609-17.
PMID: 16217746
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An ELISA method for the detection and quantification of human heparanase.
2006
Biochem Biophys Res Commun. 2006 Mar 24;341(4):958-63. Epub 2006 Jan 24.
PMID: 16458254
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Laparoscopic diagnostic peritoneal lavage (L-DPL): A method for evaluation of penetrating abdominal stab wounds.
2006
Dan Hershko, MDAuthors : Krausz MM, Abbou B, Hershko DD, Mahajna A, Duek DS, Bishara B, Israelit SH.
World J Emerg Surg. 2006 Mar 24;1:3.
PMID: 16759402
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Sentinel lymph node biopsy in thin melanoma patients.
2006
Dan Hershko, MDAuthors : Hershko DD, Robb BW, Lowy AM, Ahmad SA, Ramadas GH, Soldano DA, Sussman JJ.
J Surg Oncol. 2006 Mar 15;93(4):279-85.
PMID: 16496355
|
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Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin.
2006
Israel Vlodavsky, PhDAuthors : Nasser NJ, Sarig G, Brenner B, Nevo E, Goldshmidt O, Zcharia E, Li JP, Vlodavsky I.
J Thromb Haemost. 2006 Mar;4(3):560-5.
PMID: 16460439
|
|
Peroxynitrite induces an alternative NF-kB activation pathway in L8 rat myoblasts
2006
Antioxid Redox Signal 8, 639-652.
|
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Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction.
2006
Stem Cells. 2006 Feb;24(2):236-45. Epub 2005 Dec 1.
PMID: 16322641
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|
Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation.
2006
Cancer Res. 2006 Feb 1;66(3):1455-63.
PMID: 16452201
|
|
The neuropilins and their role in tumorigenesis and tumor progression.
2006
Gera Neufeld, PhDAuthors : Guttmann-Raviv N, Kessler O, Shraga-Heled N, Lange T, Herzog Y, Neufeld G.
Cancer Lett. 2006 Jan 8;231(1):1-11. Review.
PMID: 16356825
|
|
Derivation and maintenance of human embryonic stem cells.
2006
Methods Mol Biol. 2006;331:43-53.
|
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Feeder-free culture of human embryonic stem cells.
2006
Methods Enzymol. 2006;420:37-49.
|
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Maintenance of human embryonic stem cells in animal serum- and feeder layer-free culture conditions.
2006
Methods Mol Biol. 2006;331:105-13.
PMID: 16881512
|
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Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis.
2006
Int J Biochem Cell Biol.2006;38(12):2018-39.
|
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The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells.
2006
Breast Cancer Res. 2006;8(4):R46.
|
|
Tissue engineering using human embryonic stem cells.
2006
Methods Enzymol. 2006;420:303-15.
|
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Vascular cells.
2006
Methods Enzymol. 2006;418:252-66
|
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The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs.
2005
Genes Dev. 2005 Dec 15;19(24):3004-16.
PMID: 16357218
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A new targeting approach for breast cancer gene therapy using the Heparanase promoter.
2005
Israel Vlodavsky, PhDAuthors : Breidenbach M, Rein DT, Schondorf T, Khan KN, Herrmann I, Schmidt T, Reynolds PN, Vlodavsky I, Haviv YS, Curiel DT.
Cancer Lett. 2005 Nov 2; [Epub ahead of print]
PMID: 16271435
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Adaptive evolution of heparanase in hypoxia-tolerant Spalax: gene cloning and identification of a unique splice variant.
2005
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15161-6. Epub 2005 Oct 4.
PMID: 16204381
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Leukomogenic factors downregulate heparanase expression in acute myeloid leukemia cells.
2005
Israel Vlodavsky, PhDAuthors : Eshel R, Ben-Zaken O, Vainas O, Nadir Y, Minucci S, Polliack A, Naparstek E, Vlodavsky I, Katz BZ.
Biochem Biophys Res Commun. 2005 Oct 7;335(4):1115-22.
PMID: 16112651
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Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2.
2005
Gera Neufeld, PhDAuthors : Vadasz Z, Kessler O, Akiri G, Gengrinovitch S, Kagan HM, Baruch Y, Izhak OB, Neufeld G.
J Hepatol. 2005 Sep;43(3):499-507.
PMID: 16023247
|
|
CD133-positive hematopoietic stem cell "stemness" genes contain many genes mutated or abnormally expressed in leukemia.
2005
Joseph Itskovitz-Eldor, MD, DScAuthors : Toren A, Bielorai B, Jacob-Hirsch J, Fisher T, Kreiser D, Moran O, Zeligson S, Givol D, Yitzhaky A, Itskovitz-Eldor J, Kventsel I, Rosenthal E, Amariglio N, Rechavi G.
Stem Cells. 2005 Sep;23(8):1142-53.
PMID: 16140871
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Bowel preparation is associated with spillage of bowel contents in colorectal surgery.
2005
Dan Hershko, MDAuthors : Mahajna A, Krausz M, Rosin D, Shabtai M, Hershko D, Ayalon A, Zmora O.
Dis Colon Rectum. 2005 Aug;48(8):1626-31.
PMID: 15981063
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Nucleofection of human embryonic stem cells.
2005
Stem Cells Dev. 2005 Aug;14(4):378-83.
PMID: 16137226
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Society's contribution to assisted reproductive technology abuse.
2005
Hum Reprod. 2005 Aug;20(8):2362. No abstract available.
PMID: 16024541
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Homodimeric MyoD preferentially binds tetraplex structures of regulatory sequences of muscle-specific genes.
2005
Eyal Bengal, PhDAuthors : Etzioni S, Yafe A, Khateb S, Weisman-Shomer P, Bengal E, Fry M.
J Biol Chem. 2005 Jul 22;280(29):26805-12. Epub 2005 May 27.
PMID: 15923190
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The expression of the ubiquitin ligase subunit Cks1 in human breast cancer.
2005
Dan Hershko, MDAuthors : Slotky M, Shapira M, Ben-Izhak O, Linn S, Futerman B, Tsalic M, Hershko DD.
Breast Cancer Res. 2005;7(5):R737-44. Epub 2005 Jul 19.
PMID: 16168119
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Transanal endoscopic microsurgery for rectal cancer.
2005
Isr Med Assoc J. 2005 Jul;7(7):435-8.
PMID: 16011058
|
|
Molecular analysis of cardiomyocytes derived from human embryonic stem cells.
2005
Dev Growth Differ. 2005 Jun;47(5):295-306.
PMID: 16026538
|
|
No evidence for infection of human embryonic stem cells by feeder cell-derived murine leukemia viruses.
2005
Joseph Itskovitz-Eldor, MD, DScAuthors : Amit M, Winkler ME, Menke S, Bruning E, Buscher K, Denner J, Haverich A, Itskovitz-Eldor J, Martin U.
Stem Cells. 2005 Jun-Jul;23(6):761-71.
PMID: 15917472
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In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis.
2005
Israel Vlodavsky, PhDAuthors : Li JP, Galvis ML, Gong F, Zhang X, Zcharia E, Metzger S, Vlodavsky I, Kisilevsky R, Lindahl U.
Proc Natl Acad Sci U S A. 2005 May 3;102(18):6473-7. Epub 2005 Apr 20.
PMID: 15843464
|
|
Heparanase processing by lysosomal/endosomal protein preparation
2005
FEBS Lett. 2005 Apr 25;579(11):2334-8.
PMID: 15848168
|
|
Heparanase regulates murine hair growth.
2005
Israel Vlodavsky, PhDAuthors : Zcharia E, Philp D, Edovitsky E, Aingorn H, Metzger S, Kleinman HK, Vlodavsky I, Elkin M.
Am J Pathol. 2005 Apr;166(4):999-1008.
PMID: 15793281
|
|
Segregation of arterial and venous markers in subpopulations of blood islands before vessel formation.
2005
Dev Dyn. 2005 Apr;232(4):1047-55.
PMID: 15739224
|
|
The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma.
2005
Dan Hershko, MDAuthors : Shapira M, Ben-Izhak O, Linn S, Futerman B, Minkov I, Hershko DD.
Cancer. 2005 Apr 1;103(7):1336-46.
PMID: 15717322
|
|
The role of heparanase in lymph node metastatic dissemination: dynamic contrast-enhanced MRI of Eb lymphoma in mice.
2005
Israel Vlodavsky, PhDAuthors : Dafni H, Cohen B, Ziv K, Israely T, Goldshmidt O, Nevo N, Harmelin A, Vlodavsky I, Neeman M.
Neoplasia. 2005 Mar;7(3):224-33.
PMID: 15799822
|
|
Decreased expression of heparanase in glioblastoma multiforme.
2005
J Neurosurg. 2005 Mar;102(3):513-21.
PMID: 15796387
|
|
RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity.
2005
Ami Aronheim, PhDAuthors : Frankel P, Aronheim A, Kavanagh E, Balda MS, Matter K, Bunney TD, Marshall CJ.
EMBO J. 2005 Jan 12;24(1):54-62. Epub 2004 Dec 9.
PMID: 15592429
|
|
Bmp signals promote gene expression in the intermediate mesoderm in a dose-dependent, cell-autonomous, and translation-dependent manner
2005
Dev Bio 288, 113-125.
|
|
Functional properties of human embryonic stem cell-derived cardiomyocytes.
2005
Ann N Y Acad Sci. 2005 Jun;1047:66-75.
PMID: 16093485
|
|
Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors.
2005
Amir Orian, MD, PhDAuthors : Orian A, Grewal SS, Knoepfler PS, Edgar BA, Parkhurst SM, Eisenman RN.
Cold Spring Harb Symp Quant Biol. 2005;70:299-307.
|
|
HVEGF165 increases survival of transplanted hepatocytes within portal radicles: suggested mechanism for early cell engraftment.
2005
Gera Neufeld, PhDAuthors : Shani-Peretz H, Tsiperson V, Shoshani G, Veitzman E, Neufeld G, Baruch Y.
Cell Transplant. 2005;14(1):49-57.
PMID: 15789662
|
|
Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase.
2005
Israel Vlodavsky, PhDAuthors : Levy-Adam F, Abboud-Jarrous G, Guerrini M, Beccati D, Vlodavsky I, Ilan N.
J Biol Chem ;280:20457-20466.
|
|
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.
2005
Nat Cell Biol ;7:295-302.
|
|
p38 MAP kinase regulates the expression of XMyf5 and affects distinct myogenic programs during Xenopus development.
2005
Dev Biol;288:73-86.
|
|
PADMA-28, a traditional Tibetan herbal preparation, blocks cellular responses to bFGF and IGF-I.
2005
Israel Vlodavsky, PhDAuthors : Navab R, Aingorn H, Fallavollita L, Sallon S, Mechoulam R, Ginsburg I, Vlodavsky I, Brodt P.
Inflammopharmacology. 2004;12(4):373-89.
PMID: 15901415
|
|
Semaphorins in cancer.
2005
Gera Neufeld, PhDAuthors : Neufeld G, Shraga-Heled N, Lange T, Guttmann-Raviv N, Herzog Y, Kessler O.
Front Biosci. 2005 Jan 1;10:751-60. Print 2005 Jan 1.
PMID: 15569615
|
|
Site-directed mutagenesis, proteolytic cleavage, and activation of human proheparanase.
2005
Israel Vlodavsky, PhDAuthors : Abboud-Jarrous G, Rangini-Guetta Z, Aingorn H, Atzmon R, Elgavish S, Peretz T, and Vlodavsky,I.
J Biol Chem 280: 13568-13575.
|
|
YND1 interacts with CDC55 and is a novel mediator of E4orf4-induced toxicity.
2005
J Biol Chem ;280:41270-41277.
|
|
A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation.
2004
Eyal Bengal, PhDAuthors : Penn BH, Bergstrom DA, Dilworth J, Bengal E, Tapscott SJ.
Genes Dev ;18:2348-2353.
|
|
Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma.
2004
Dan Hershko, MDAuthors : Shapira M, Ben-Izhak O, Bishara B, Futerman B, Minkov I, Krausz MM, Pagano M, Hershko DD.
Cancer ;100:1615-1621.
|
|
Feeder layer- and serum-free culture of human embryonic stem cells.
2004
Biol Reprod ;70:837-845.
|
|
Hairy transcriptional repression targets and cofactor recruitment in Drosophila.
2004
Amir Orian, MD, PhDAuthors : Bianchi-Frias D, Orian A, Delrow J, Vazquez J, Rosales-Nieves AE, Parkhurst SM.
PLoS Biology ;2:e178.
|
|
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis.
2004
J Natl Cancer Inst ;96:1219-1230.
|
|
Recruitment of ectodermal attachment cells via an EGFR-dependent mechanism during the organogenesis of Drosophila proprioceptors.
2004
Dev Cell ;7:241-250.
|
|
Rpb4 and Rpb7: subunits of RNA polymerase II and beyond.
2004
Trends Biochem Sci;29:674-681.
|
|
Semaphorin-3F is an inhibitor of tumor angiogenesis.
2004
Gera Neufeld, PhDAuthors : Kessler O, Shraga-Heled N, Lange T, Gutmann-Raviv N, Sabo E, Baruch L, Machluf M, Neufeld G.
Cancer Res ;64:1008-1015.
|
|
The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene.
2004
J Biol Chem ;279:5708-5715.
|
|
The Meis3 protein and retinoid signaling interact to pattern the Xenopus hindbrain.
2004
Dale Frank, PhDAuthors : Dibner C, Elias S, Ofir R, Souopgui J, Kolm PJ, Sive H, Pieler T, Frank D.
Dev Biol ;271:75-86.
|
|
The scaffolding A/Tpd3 subunit and high phosphatase activity are dispensable for Cdc55 function in the Saccharomyces cerevisiae spindle checkpoint and in cytokinesis.
2004
J Biol Chem ;279:48598-48606.
|
|
Xenopus Meis3 protein forms a hindbrain-inducing center by activating FGF/MAP kinase and PCP pathways.
2004
Development;131:153-163.
|
|
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network.
2003
Amir Orian, MD, PhDAuthors : Orian A, van Steensel B, Delrow J, Bussemaker HJ, Li L, Sawado T, Williams E, Loo LWM, Cowley SM, Yost C, Pierce S, Edgar BA, Parkhurst SM, Eisenman RN.
Genes Dev;17:1101-1114.
|
|
Human embryonic stem cells as an in vitro model for human vascular development and the induction of vascular differentiation.
2003
Lab Invest ;83:1811-1820.
|
|
Lysyl oxidase-related protein-1 promotes tumor fibrosis and tumor progression in vivo.
2003
Gera Neufeld, PhDAuthors : Akiri G, Sabo E, Dafni H, Vadasz Z, Kartvelishvily Y, Gan N, Kessler O, Cohen T, Resnick M, Neeman M, Neufeld G.
Cancer Res ;63:1657-1666.
|
|
Multiple roles for u-turn/ventral veinless in the development of Drosophila PNS.
2003
Development ;130:2467-2478.
|
|
Rpb4p, a subunit of RNA polymerase II, mediates mRNA export during stress.
2003
Mol Biol Cell ;14:2744-2755.
|
|
The mitogen-activated protein kinase cascade promotes myoblast cell survival by stabilizing the cyclin-dependent kinase inhibitor, p21WAF1 protein.
2003
J Biol Chem ;278:21221-21231.
|
|
Differential targeting of the stress MAPKs to the c-Jun dimerization protein 2.
2002
Biochem J ;368:939-945.
|
|
Induction of terminal differentiation by the c-Jun dimerization protein, JDP2, in C2 myoblasts and rhabdomyosarcoma cells.
2002
J Biol Chem ;277:40043-40054.
|
|
The Neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis.
2002
Gera Neufeld, PhDAuthors : Neufeld G, Cohen T, Shraga N, Lange T, Kessler O, Herzog Y.
Trends Cardiovasc Med;12:13-19.
|
|
Tail vein assay of cancer metastasis.
2001
Curr Protoc Cell Biol. 2001 Nov;Chapter 19:Unit 19.2.
PMID: 18228345
|
|
Preparation of extracellular matrices produced by cultured corneal endothelial and PF-HR9 endodermal cells.
2001
Curr Protoc Cell Biol. 2001 May;Chapter 10:Unit 10.4.
|
|
Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome.
2001
J Cell Biol ;154:331-344.
|
|
Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development.
2001
Development ;128:3405-3413.
|
|
Inverse relation between levels of p27Kip1 and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas.
2001
Dan Hershko, MDAuthors : Hershko D, Bornstein G, Ben-Izhak O, Carrano A, Pagano M, Krausz MM, Hershko A.
Cancer ;91:1745-1751.
|
|
XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos.
2001
Development ;128:3415-3426.
|
|
Embryonic stem cell lines derived from human blastocysts.
1998
Science ;282:1145-1147.
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|
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