Autoimmune,Inflammatory and Infectious Disease

Protein denitrosylation: enzymatic mechanisms and cellular functions

Psoriasis patients generate increased serum levels of autoantibodies to tumor necrosis factor-alpha and interferon-alpha

The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis

Insights into the mechanism of DNA recognition by the methylated LINE binding protein EhMLBP of Entamoeba histolytica

A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2

A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular‭ (‬E3‭) ‬domain of CCR2‭ ‬neutralizes‭ ‬the biological activity of CCL2

Selective autoantibody production against CCL3‭ ‬is associated with human type 1‭ ‬diabetes mellitus and serves as a novel biomarker for its diagnosis

The effect of 100% oxygen on intestinal preservation and recovery following ischemia-reperfusion injury in rats

Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor

TOLL-like receptor ligands stimulate aberrant class switch recombination in early B cell precursors

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

EhMLBP is an essential constituent of the Entamoeba histolytica epigenetic machinery and a potential drug target

Hypoxia enhances lysosomal TNF-α degradation in mouse peritoneal macrophages

What do unicellular organisms teach us about DNA methylation?

Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins

Trichostatin A regulates peroxiredoxin expression and virulence of the parasite Entamoeba histolytica.

Progress and prospects of gene inactivation in Entamoeba histolytica.

Class switch recombination: a friend and a foe.

Native and fragmented fibronectin oppositely modulate monocyte secretion of MMP-9

SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK.

Dual role of SLP-76 in mediating T cell receptor-induced activation of phospholipase C-gamma1.

B cell receptor editing in tolerance and autoimmunity.

Genome-wide analysis of mRNA polysomal profiles with spotted DNA microarrays.

Coadministration of plasmid DNA constructs encoding an encephalitogenic determinant and IL-10 elicits regulatory T cell-mediated protective immunity in the central nervous system.

Sensing DNA methylation in the protozoan parasite Entamoeba histolytica.

Modulation of matrix metalloproteinase-9 (MMP-9) secretion in B lymphopoiesis.

A Pak- and Pix-dependent branch of the SDF-1alpha signalling pathway mediates T cell chemotaxis across restrictive barriers.

DNA methylation and targeting of LINE retrotransposons in Entamoeba histolytica and Entamoeba invadens.

Pleiotropic phenotype in Entamoeba histolytica overexpressing DNA methyltransferase (Ehmeth).

Hypoxia reduces the output of matrix metalloproteinase-9 (MMP-9) in monocytes by inhibiting its secretion and elevating membranal association

Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation

Beneficial autoimmunity participates in the regulation of rheumatoid arthritis.

The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs.

Single point mutations in the zinc finger motifs of the human immunodeficiency virus type 1 nucleocapsid alter RNA binding specificities of the gag protein and enhance packaging and infectivity.

Molecular characterization of Entamoeba histolytica Rnase III and AGO2, two RNA interference hallmark proteins.

Targeted overexpression of IL-18 binding protein at the central nervous system overrides flexibility in functional polarization of antigen-specific Th2 cells.

T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.

Naive, effector, and memory T lymphocytes efficiently scan dendritic cells in vivo: contact frequency in T cell zones of secondary lymphoid organs does not depend on LFA-1 expression and facilitates

Antigen receptor signaling competence and the determination of B cell fate in B-lymphopoiesis.

CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing.

Entamoeba histolytica DNA methyltransferase (Ehmeth) is a nuclear matrix protein that binds EhMRS2, a DNA that includes a scaffold/matrix attachment region (S/MAR).

Epigenetic and classical activation of Entamoeba histolytica heat shock protein 100 (EHsp100) expression.

T cell receptor-induced activation of phospholipase C-γ1 depends on a sequence-independent function of the P-I region of SLP-76.

Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite Entamoeba histolytica.

Modification of ligandindependent B cell receptor tonic signals activates receptor editing in immature B lymphocytes.

A failsafe mechanism for negative selection of isotype-switched B cell precursors is regulated by the Fas/FasL pathway.

Beneficial autoimmunity to proinflammatory mediators restrains the consequences of self-destructive immunity.

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

Tr1 cell-dependent active tolerance blunts the pathogenic effects of determinant spreading.

A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.

Identification of a phospholipase C-γ1 (PLC- γ1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-γ1 and NFAT

C-C chemokineencoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis.

Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo.

T cell differentiation: a mechanistic view.