The Central Nervous System in Health and Disease

Up-regulation of‭ ‬Hypoxia-Inducible Factor‭ (‬HIF‭) -‬1alpha and HIF-Target Genes in Cortical Neurons by the Novel Multifunctional Iron Chelator Anti-Alzheimer Drug‭, ‬M30

The Neuroprotective Mechanism of 1-‭(‬R‭)-‬Aminoindan‭, ‬the Major Metabolite of the Anti-Parkinsonian Drug Rasagiline

Differences in‭ ‬TMS-evoked responses between schizophrenia patients and healthy controls can be observed without a dedicated EEG system

SAFETY EVALUATION OF REPEATED INTRAVITREAL INJECTIONS OF BEVACIZUMAB AND RANIBIZUMAB IN RABBIT EYES

Limited Potentiation of Blood Pressure in Response to Oral Tyramine by the Anti-Parkinson Brain Selective Multifunctional Monoamine Oxidase-AB Inhibitor, M30

Salivary analysis of oral cancer biomarkers

DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2

Effects of dextromethorphan/quinidine on auditory event-related potentials in multiple sclerosis patients with pseudobulbar affect

Pilot controlled trial of D-serine for the treatment of post-traumatic‭ ‬stress disorder

Seizure relapse and development of drug resistance following long-term seizure remission

The interplay between mitochondrial complex I, dopamine and Sp1 in schizophrenia

Encoding and decoding bursts by NMDA spikes in basal dendrites of layer 5 pyramidal neurons

Parkinson's disease tremor is diminished with relaxation guided imagery

A sporadic parkinson's disease model via silencing of the ubiquitin-proteasome/E3-ligase component, SKP1A

Neuroprotective molecular mechanisms of (-)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties

Physical stress differs from psychosocial stress in the pattern and time-course of behavioral responses, serum corticosterone and expression of plasticity-related genes in the rat

Estradiol modulates uterine 18 kDa translocator protein gene expression in uterus and kidney of rats

Estradiol modulates uterine 18‭ ‬kDa translocator protein gene expression in uterus and kidney of rats

Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

Cortical evoked potentials to an auditory illusion: Binaural beats

Restoration of Nigrostriatal Dopamine Neurons in Post-MPTP Treatment by the Novel Multifunctional Brain-Permeable Iron Chelator-Monoamine Oxidase Inhibitor Drug, M30.

Mitochondrial complex I as a novel target for intraneuronal DA: modulation of respiration in intact cells

Long-term relationships between synaptic tenacity‭, ‬synaptic remodeling‭, ‬and network activity

Auditory and multisensory responses in the tectofugal pathway of the barn owl

Mitochondrial complex I subunits are altered in rats with neonatal ventral hippocampal damage but not in rats exposed to oxygen restriction at neonatal age

Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses

Multisensory enhancement in the optic tectum of the barn owl: spike count and spike timing

CoCl(2) Induces Apoptosis via the 18 kDa Translocator Protein in U118MG Human Glioblastoma Cells

Genomic and proteomic study to survey the mechanism of action of the anti-Parkinson's disease drug, rasagiline compared with selegiline, in the rat midbrain

Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane

Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses

Exchange and redistribution dynamics of the cytoskeleton of the active zone molecule bassoon

Biomarkers for evaluation of clinical efficacy of multipotential neuroprotective drugs for Alzheimer's and Parkinson's diseases

Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs

Multifunctional pharmacotherapy: what can we learn from study of selective serotonin reuptake inhibitor augmentation of antipsychotics in negative-symptom schizophrenia?

Neuroprotective effect of Ro5-4864 following brain injury

Translation towards personalized medicine in Multiple Sclerosis

Testing retinal toxicity of drugs in animal models using electrophysiological and morphological techniques

Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression

Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG)

The neuroprotective effect of ladostigil against hydrogen peroxide-mediated cytotoxicity

The Novel Cholinesterase-Monoamine Oxidase Inhibitor and Antioxidant, Ladostigil, Confers Neuroprotection in Neuroblastoma Cells and Aged Rats

Brain responses to verbal stimuli among multiple sclerosis patients with pseudobulbar affect

The application of proteomics for studying the neurorescue activity of the polyphenol (-)-epigallocatechin-3-gallate

Targeting multiple neurodegenerative diseases etiologies with multimodal-acting green tea catechins

Brain iron deficiency and excess; cognitive impairment and neurodegeneration with involvement of striatum and hippocampus

Impact of exposure to war stress on exacerbations of multiple sclerosis

Targeting multiple neurodegenerative diseases etiologies with multimodal-acting green tea catechins

The effect of oxygenation level on cerebral post-traumatic apoptotsis is modulated by the 18-kDa translocator protein (also known as peripheral-type benzodiazepine receptor) in a rat model of cortical contusion

D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration

Perceptual visual grouping under inattention: electrophysiological functional imaging

Stimulus-specific adaptations in the gaze control system of the barn owl.

Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: Relevance to dopamine pathology in schizophrenia

The auditory P50 component to onset and offset of sound.

Quantifying the response to antiepileptic drugs: effect of past treatment history.

The influence of clozapine treatment and other antipsychotics on the 18 kDa translocator protein, formerly named the peripheral-type benzodiazepine receptor, and steroid production.

Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy.

Novel multifunctional anti-Alzheimer drugs with various CNS neurotransmitter targets and neuroprotective moieties.

NMDA Receptor Regulation by D: -serine: New

NMDA receptor regulation by D-serine: new findings and perspectives.

Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2

Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.

Otoacoustic Emissions in Early Noise-Induced Hearing Loss.

A novel approach of proteomics and transcriptomics to study the mechanism of action of the antioxidant-iron chelator green tea polyphenol (-)-epigallocatechin-3-gallate.

Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers.

Evaluation of intravitreal kenalog toxicity in humans.

A novel isoform of acetylcholinesterase exacerbates photoreceptors death after photic stress.

Cellular mechanisms underlying antiepileptic effects of low- and high-frequency electrical stimulation in acute epilepsy in neocortical brain slices in vitro.

Categorical Perception of Speech (VOT) and Analogous Non-Speech (FOT) Signals: Behavioral and Electrophysiological Correlates.

Properties of basal dendrites of layer 5 pyramidal neurons: a direct patch-clamp recording study.

A model of MPTP-induced Parkinson's disease in the goldfish.

Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism.

Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response.

Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment.

Implications of co-morbidity for etiology and treatment of neurodegenerative diseases with multifunctional neuroprotective-neurorescue drugs; ladostigil.

Patterns of motor activity in the isolated nerve cord of the octopus arm.

Plasticity compartments in basal dendrites of neocortical pyramidal neurons.

Cardiovascular responses to combined treatment with selective monoamine oxidase type B inhibitors and L-DOPA in the rat.

Multifunctional drugs with different CNS targets for neuropsychiatric disorders.

Synapse development: still looking for the forest, still lost in the trees.

D-serine regulation of NMDA receptor activity.

Local Sharing as a Predominant Determinant of Synaptic Matrix Molecular Dynamics.

Multifunctional neuroprotective drugs targeting monoamine oxidase inhibition, iron chelation, adenosine receptors, and cholinergic and glutamatergic action for neurodegenerative diseases.

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function.

Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemase.

Preface - special issue: neuromelanin.

The copper chelator, D-penicillamine, does not attenuate MPTP induced dopamine depletion in mice.

The effect of chronic co-administration of fluvoxamine and haloperidol compared to clozapine on the GABA system in the rat frontal cortex.

The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development.

Striatal dopa and glucose metabolism in PD patients with freezing of gait.

Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors

Adaptation in the auditory space map of the barn owl.

Hypotrichosis with juvenile macular dystrophy: clinical and electrophysiological assessment of visual function.

Retinal toxicity of indocyanine green in albino rabbits.

Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries.

Light-induced changes in spike synchronization between coupled ON direction selective ganglion cells in the mammalian retina

Reduction of iron-regulated amyloid precursor protein and beta-amyloid peptide by (-)-epigallocatechin-3-gallate in cell cultures: implications for iron chelation in Alzheimer's disease.

The therapeutic potential of monoamine oxidase inhibitors.

Electrophysiologic and retinal penetration studies following intravitreal injection of bevacizumab (Avastin).

The effects of prostaglandin F2alpha treatment on peripheral-type benzodiazepine receptors in the ovary and uterus during pseudopregnancy of rats.

Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders.

Involvement of multiple survival signal transduction pathways in the neuroprotective, neurorescue and APP processing activity of rasagiline and its propargyl moiety.

M30, a novel multifunctional neuroprotective drug with potent iron chelating and brain selective monoamine oxidase-ab inhibitory activity for Parkinson's disease.

Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness.

NMDA spikes in basal dendrites of cortical pyramidal neurons.

Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine.

D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices.

Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition.

Synthesis and evaluation of peptidic metal chelators for neuroprotection in neurodegenerative diseases.

The neurochemical and behavioral effects of the novel cholinesterase-monoamine oxidase inhibitor, ladostigil, in response to L-dopa and L-tryptophan, in rats.

Proceedings from the "Third International Conference on Mechanism of Action of Nutraceuticals".

Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70.

Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway.

The peripheral-type benzodiazepine receptor and tumorigenicity: isoquinoline binding protein (IBP) antisense knockdown in the C6 glioma cell line.

Green tea polyphenol (-)-epigallocatechin-3-gallate induces neurorescue of long-term serum-deprived PC12 cells and promotes neurite outgrowth.

Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline.

Characterization of the neuroprotective activity of rasagiline in cerebellar granule cells.

Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity.

Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway.

Neurophysiological correlates of subjective significance.

Novel potential neuroprotective agents with both iron chelating and amino acid-based derivatives targeting central nervous system neurons.

Serine racemase modulates intracellular D-serine levels through an α,β-elimination activity.

The 'F-complex' and MMN tap different aspects of deviance.

Activation of a calcium-activated cation current during epileptiform discharges and its possible role in sustaining seizure-like events in neocortical slices.

Auditory middle-latency components to fusion of speech elements forming an auditory object.

Cellular and molecular mechanisms of presynaptic assembly.

Computational subunits in thin dendrites of pyramidal cells.

Development and maintenance of aligned visualauditory maps in the midbrain. In: Handbook of Multisensory Processes. In: Calvert G, Spence C, Stein BE, editors.

Genomic profiling of interpopulation diversity guides prioritization of candidate-genes for autoimmunity.

Homogeneity and diversity of color-opponent horizontal cells in the turtle retina: Consequences for potential wavelength discrimination.

Iron, brain ageing and neurodegenerative disorders.

Nitric oxide modulates the transfer function between cones and horizontal cells during changing conditions of ambient illumination.

Peripheral benzodiazepine receptor antisense knockout increases tumorigenicity of MA-10 Leydig cells in vivo and in vitro.

Peripheral-type benzodiazepine receptor density and in vitro tumorigenicity of glioma cell lines.

Postsynaptic density assembly is fundamentally different from presynaptic active zone assembly.

NADPH diaphorase activity in the rat retina during the early stages of experimental diabetes.

Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons.

Unitary assembly of presynaptic active zones from piccolo-bassoon transport vesicles.

Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine.

Gated visual input to the central auditory system.

Inter-ictal- and ictal-like epileptic discharges in the dendritic tree of neocortical pyramidal neurons.

Pharmacogenetic development of personalized medicine: multiple sclerosis treatment as a model.

Control of octopus arm extension by a peripheral motor program.

Matrix metalloproteinases and their tissue inhibitors as markers of disease subtype and response to interferon-beta therapy in relapsing and secondary-progressive multiple sclerosis patients.