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Cardiovascular Biology in Health and Disease

 
Involvement of‭ ‬Heparanase in early pregnancy losses
2009
Benjamin Brenner, MD
Authors : Nadir Y‭, ‬Henig I‭, ‬Naroditzky I‭, ‬Paz B‭, ‬Vlodavsky I‭, ‬Brenner B‭.
Thromb Res‭. ‬2009‭ ‬Dec 21‭. [‬Epub ahead of print‭]
 
Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells
2009
Ofer Binah, PhD
Authors : Germanguz I‭, ‬Sedan O‭, ‬Zeevi-Levin N‭, ‬Shtreichman R‭, ‬Barak E‭, ‬Ziskind A‭, ‬Eliyahu S‭, ‬Meiry G‭, ‬Amit M‭, ‬Itskovitz-Eldor J‭, ‬Binah O‭.
J Cell Mol Med‭. ‬2009‭ ‬Dec 11‭. [‬Epub ahead of print‭]
 
Increased macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2‭ (‬PON2‭)‬ expression in Delta6-desaturase knockout‭ (‬6-DS KO‭) ‬mice‭: ‬Beneficial effects of arachidonic acid
2009
Michael Aviram, DSc
Authors : Rosenblat M‭, ‬Volkova N‭, ‬Roqueta-Rivera M‭, ‬Nakamura MT‭, ‬Aviram M‭. ‬
Atherosclerosis‭. ‬2009‭ ‬Dec 1‭. [‬Epub ahead of print‭]
 
High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx
2009
Michael Aviram, DSc
Authors : Gantman A, Fuhrman B, Aviram M, Hayek T.
Biochem Biophys Res Commun. 2009 Nov 23.
 
Nitric oxide and superoxide dismutase modulate endothelial progenitor cell function in type 2 diabetes mellitus
2009
Benjamin Brenner, MD
Authors : Hamed S, Brenner B, Aharon A, Daoud D, Roguin A.
Cardiovasc Diabetol. 2009 Oct 30;8:56
 
Urinary Excretion of Endothelin Receptors ET(A) and ET(B) in Hypertensive Patients and Normotensive Subjects
2009
Aaron Hoffman, MD
Authors : Karram T, Khamaisi M, Bishara B, Ramadan R, Nitecki S, Ben-Izhak O, Meretyk S, Winaver J, Heyman SN, Hoffman A, Abassi Z.
Kidney Blood Press Res. 2009 32(4):293-303.
 
Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells
2009
Lior Gepstein, MD, PhD
Authors : Zwi L, Caspi O, Arbel G, Huber I, Gepstein A, Park IH, Gepstein L.
Circulation. 2009 Sep 28. [Epub ahead of print]
 
Lipoprotein interactions with chromatic membranes as a novel marker for oxidative stress - related diseases
2009
Michael Aviram, DSc
Authors : Hanin-Avraham N, Fuhrman B, Mech-Dorosz A, Kolusheva S, Porgador A, Aviram M, Jelinek R.
Biochim Biophys Acta. 2009 Sep 28. [Epub ahead of print]
 
Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with Diabetes and the Hp 2-2 genotype
2009
Andrew P. Levy, MD, PhD, FACC
Authors : Asleh R, Levy A.
Antioxid Redox Signal. 2009 Sep 21. [Epub ahead of print]
 
Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: Studies in vitro and in diabetic patients
2009
Michael Aviram, DSc
Authors : Fuhrman B, Volkova N, Aviram M.
Nutrition. 2009 Sep 15. [Epub ahead of print]
 
Effects of date (Phoenix dactylifera L., Medjool or Hallawi Variety) consumption by healthy subjects on serum glucose and lipid levels and on serum oxidative status: a pilot study
2009
Michael Aviram, DSc
Authors : Rock W, Rosenblat M, Borochov-Neori H, Volkova N, Judeinstein S, Elias M, Aviram M.
J Agric Food Chem. 2009 Sep 9;57(17):8010-7.
 
Paraoxonase 1(PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: A role for PPAR-gamma pathway
2009
Michael Aviram, DSc
Authors : Khateeb J, Gantman A, Kreitenberg AJ, Aviram M, Fuhrman B.
Atherosclerosis. 2009 Sep 6. [Epub ahead of print]
 
The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque.
2009
Andrew P. Levy, MD, PhD, FACC
Authors : Kalet-Litman S, Moreno PR, Levy AP.
Atherosclerosis. 2009 Sep 6. [Epub ahead of print]
 
Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: Studies in PON2-deficient mice
2009
Michael Aviram, DSc
Authors : Meilin E, Aviram M, Hayek T.
Atherosclerosis. 2009 Aug 8. [Epub ahead of print]
 
Haptoglobin :basic and clinical aspects
2009
Andrew P. Levy, MD, PhD, FACC
Authors : Levy A, Asleh R, Blum S, Levy N, Miller-Lotan R, Kalet-Litman S, Anbinder Y, Lache O, Nakhoul F, Asaf R, Farbstein D, Pollak M, Soloveichik Y, Strauss M, Alshiek J, Livshits A, Schwartz A, Awad H, Jad K, Goldenstein H.
Antioxid Redox Signal. 2009 Aug 6
 
Transplantation of a Tissue-Engineered Human Vascularized Cardiac Muscle
2009
Lior Gepstein, MD, PhD
Authors : Lesman A, Habib M, Caspi O, Gepstein A, Arbel G, Levenberg S, Gepstein L.
Tissue Eng Part A. 2009 Jul 30
 
Assessment and management of high-risk pregnancies in women with thrombophilia
2009
Benjamin Brenner, MD
Authors : Sarig G, Vidergor G, Brenner B.
Blood Rev. 2009 Jul;23(4):143-7
 
Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signaling cascade mediated by the PDGFR-{beta}
2009
Michael Aviram, DSc
Authors : Fuhrman B, Gantman A, Khateeb J, Volkova N, Horke S, Kiyan J, Dumler I, Aviram M.
Cardiovasc Res. 2009 Jun 4.
 
Haptoglobin genotype is a determinant of survival and cardiac remodeling after myocardial infarction in diabetic mice
2009
Andrew P. Levy, MD, PhD, FACC
Authors : Asaf R, Blum S, Roguin A, Kalet-Litman S, Kheir J, Frisch A, Miller-Lotan R,
Cardiovasc Diabetol. 2009 Jun 2;8:29.
 
Vitamin K-dependent coagulation factors deficiency
2009
Benjamin Brenner, MD
Authors : Brenner B, Kuperman AA, Watzka M, Oldenburg J.
Semin Thromb Hemost. 2009 Jun;35(4):439-46
 
Antioxidants in the prevention of Atherosclerosis: The importance of proper patient selection
2009
Andrew P. Levy, MD, PhD, FACC
Authors : Levy Y, Blum S, Levy AP.
Clin Nutr. 2009 May 21.
 
Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1
2009
Michael Aviram, DSc
Authors : Rosenblat M, Coleman R, Reddy ST, Aviram M.
J Lipid Res.2009, 50(5):870-9
 
Pharmacogenomic effect of vitamin E on kidney structure and function in transgenic mice with the haptoglobin 2-2 genotype and diabetes mellitus
2009
Andrew P. Levy, MD, PhD, FACC
Authors : Nakhoul FM, Miller-Lotan R, Awad H, Asleh R, Jad K, Nakhoul N, Asaf R, Abu-Saleh N, Levy AP.
Am J Physiol Renal Physiol. 2009 Apr; 296(4):F830-8.
 
Shear stress-induced transcriptional regulation via hybrid promoters as a potential tool for promoting angiogenesis
2009
Ofer Binah, PhD
Authors : Silberman M, Barac YD, Yahav H, Wolfovitz E, Einav S, Resnick N, Binah O.
Angiogenesis. 2009 Mar 26. [Epub ahead of print]
 
Cancer and thrombosis
2009
Benjamin Brenner, MD
Authors : Brenner B.
Best Pract Res Clin Haematol. 2009 Mar;22(1):1-2.
 
Heparanase coagulation and cancer progression
2009
Benjamin Brenner, MD
Authors : Nadir Y, Brenner B.
Best Pract Res Clin Haematol. 2009 Mar;22(1):85-92. Review
 
Microparticles, thrombosis and cancer
2009
Benjamin Brenner, MD
Authors : Aharon A, Brenner B.
Best Pract Res Clin Haematol. 2009 Mar;22(1):61-9. Review
 
Tissue factor- and tissue factor pathway inhibitor-bearing microparticles in gestational vascular complications
2009
Benjamin Brenner, MD
Authors : A, Katzenell S, Tamari T, Brenner B.
J Thromb Haemost. 2009 Mar 13. [Epub ahead of print]
 
Human carotid atherosclerotic plaque increases oxidative state of macrophages and low-density lipoproteins‭, ‬whereas paraoxonase 1‭ (‬PON1‭) ‬decreases such atherogenic effects
2009
Michael Aviram, DSc
Authors : Tavori H‭, ‬Aviram M‭, ‬Khatib S‭, ‬Musa R‭, ‬Nitecki S‭, ‬Hoffman A‭, ‬Vaya J‭. ‬
Free Radic Biol Med‭. ‬2009‭ ‬Mar 1‭;‬46‭(‬5‭):‬607-15‭.
 
Impulse conduction and gap junctional remodelling by endothelin-1 in cultured neonatal rat ventricular myocytes
2009
Ofer Binah, PhD
Authors : Reisner Y, Meiry G, Zeevi-Levin N, Barac DY, Reiter I, Abassi Z, Ziv N, Kostin S, Schaper J, Rosen MR, Binah O.
J Cell Mol Med. 2009 Mar;13(3):562-73. PubMed PMID: 19374685.
 
Lipid profile and serum characteristics of the blind subterranean mole rat, Spalax
2009
Michael Aviram, DSc
Authors : Nasser NJ, Kaplan M, Nevo E, Aviram M.
PLoS ONE. 2009;4(2):e4528.
 
A photopolymerizable hydrogel for 3-D culture of human embryonic stem cell-derived cardiomyocytes and rat neonatal cardiac cells
2009
Lior Gepstein, MD, PhD
Authors : Shapira-Schweitzer K, Habib M, Gepstein L, Seliktar D.
J Mol Cell Cardiol. 2009 Feb;46(2):213-24.
 
Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies
2009
Michael Aviram, DSc
Authors : Efrat M, Rosenblat M, Mahmood S, Vaya J, Aviram M.
Atherosclerosis. 2009; 202(2):461-9.
 
Corpus luteum hemorrhage in women with bleeding disorders
2009
Benjamin Brenner, MD
Authors : Hoffman R, Brenner B.
Womens Health (Lond Engl). 2009 Jan;5(1):91-5
 
Paraoxonases role in the prevention of cardiovascular diseases
2009
Michael Aviram, DSc
Authors : Rosenblat M, Aviram M.
Biofactors. 2009;35(1):98-104.
 
Paraoxonases role in the prevention of cardiovascular diseases
2009
Michael Aviram, DSc
Authors : Rosenblat M, Aviram M.
Biofactors. 2009 Jan-Feb;35(1):98-104.
 
Prophylaxis of travel-related thrombosis in women
2009
Benjamin Brenner, MD
Authors : Brenner B.
Thromb Res. 2009;123 Suppl 3:S26-9.
 
Microparticles and placental hemostasis
2009
Benjamin Brenner, MD
Authors : Aharon A, Brenner B.
Thromb Res. 2009;123 Suppl 2:S88-92.
 
Macrophage paraoxonase 1 (PON1) binding sites
2008
Michael Aviram, DSc
Authors : Efrat M, Aviram M.
Biochem Biophys Res Commun. 2008 Nov 7;376(1):105-10. Epub 2008 Aug 30
 
Monocyte-derived microparticles and exosomes induce procoagulant and apoptotic effects on endothelial cells
2008
Benjamin Brenner, MD
Authors : Aharon A, Tamari T, Brenner B.
Thromb Haemost. 2008 Nov;100(5):878-85
 
Phenolic antioxidants and antiatherogenic effects of Marula (Sclerocarrya birrea Subsp. caffra) fruit juice in healthy humans
2008
Michael Aviram, DSc
Authors : Borochov-Neori H, Judeinstein S, Greenberg A, Fuhrman B, Attias J, Volkova N, Hayek T, Aviram M.
J Agric Food Chem. 2008 Nov 12;56(21):9884-91. Epub 2008 Oct 10
 
Correction of HDL dysfunction in individuals with diabetes and the haptoglobin 2-2 genotype
2008
Andrew P. Levy, MD, PhD, FACC
Authors : Asleh R, Blum S, Kalet-Litman S, Alshiek J, Miller-Lotan R, Asaf R, Rock W, Aviram M, Milman U, Shapira C, Abassi Z, Levy AP.
Diabetes. 2008 Oct;57(10):2794-800. Epub 2008 Jul 3
 
Mechanical load induced by glass microspheres releases angiogenic factors from neonatal rat ventricular myocytes cultures and causes arrhythmias
2008
Ofer Binah, PhD
Authors : Barac DY, Reisner Y, Silberman M, Zeevi-Levin N, Danon A, Salomon O, Shoham M, Shilkrut M, Kostin S, Schaper J, Binah O
J Cell Mol Med. 2008 Oct;12(5B):2037-51
 
Regulation of CD163 associated casein kinase II activity is haptoglobin genotype dependent
2008
Andrew P. Levy, MD, PhD, FACC
Authors : Strauss M, Levy AP.
Mol Cell Biochem. 2008 Oct;317(1-2):131-5. Epub 2008 Jun 19
 
1,4,5-Inositol Trisphosphate Operated [Ca2+]i Stores And Angiotensin-II/Endothelin-1 Signaling Pathway Are Functional In Human Embryonic Stem Cell-Derived Cardiomyocytes
2008
Ofer Binah, PhD
Authors : Sedan O, Dolnikov K, Zeevi-Levine N, Fleishmann N, Amit M, Itskovitz-Eldor J, Binah O
Stem Cells. 2008 Sep 25. [Epub ahead of print]
 
Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities
2008
Andrew P. Levy, MD, PhD, FACC  |   Michael Aviram, DSc
Authors : Rock W, Rosenblat M, Miller-Lotan R, Levy AP, Elias M, Aviram M.
J Agric Food Chem. 2008 Sep 24;56(18):8704-13. Epub 2008 Aug 30
 
TVP1022 and propargylamine protect neonatal rat ventricular myocytes against doxorubicin-induced and serum starvation-induced cardiotoxicity
2008
Ofer Binah, PhD
Authors : Kleiner Y, Bar-Am O, Amit T, Berdichevski A, Liani E, Maor G, Reiter I, Youdim MB, Binah O
J Cardiovasc Pharmacol. 2008 Sep;52(3):268-77
 
Heparanase, tissue factor, and cancer
2008
Benjamin Brenner, MD
Authors : Nadir Y, Vlodavsky I, Brenner B.
Semin Thromb Hemost. 2008 Mar;34(2):187-94. PMID: 18645924
Antiatherogenicity of extra virgin olive oil and its enrichment with green tea polyphenols in the atherosclerotic apolipoprotein-E-deficient mice: enhanced macrophage cholesterol efflux
2008
Michael Aviram, DSc
Authors : Rosenblat M, Volkova N, Coleman R, Almagor Y, Aviram M.
J Nutr Biochem. 2008 Aug;19(8):514-23. Epub 2007 Sep 27
 
Calcium handling in human embryonic stem cell-derived cardiomyocytes
2008
Lior Gepstein, MD, PhD
Authors : Satin J, Itzhaki I, Rapoport S, Schroder EA, Izu L, Arbel G, Beyar R, Balke CW, Schiller J, Gepstein L.
Stem Cells. 2008 Aug;26(8):1961-72. Epub 2008 May 15
 
Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism
2008
Michael Aviram, DSc
Authors : Fuhrman B, Khateeb J, Shiner M, Nitzan O, Karry R, Volkova N, Aviram M.
Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1361-7. Epub 2008 Apr 24
 
Controlling Ischemic Cardiovascular Disease: From Basic Mechanisms to Clinical Management.
2008
Rafael Beyar, MD, DSc
Authors : Beyar R.
Ann N Y Acad Sci. 2008 Mar;1123:232-236. PMID: 18375595 [PubMed - as supplied by publisher]
 
Drug-eluting versus bare-metal stents: when and for whom?
2008
Rafael Beyar, MD, DSc
Authors : Nikolsky E.
J Invasive Cardiol. 2008 Mar;20(3):105-6. No abstract available. PMID: 18316824 [PubMed - in process]
 
Dual therapy with statins and antioxidants is superior to statins alone in decreasing the risk of cardiovascular disease in a subgroup of middle-aged individuals with both diabetes mellitus and the haptoglobin 2-2 genotype.
2008
Andrew P. Levy, MD, PhD, FACC
Authors : Blum S, Milman U, Shapira C, Miller-Lotan R, Bennett L, Kostenko M, Landau M, Keidar S, Levy Y, Khemlin A, Radan A
Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):e18-20.
 
Experimental Molecular and Stem Cell Therapies in Cardiac Electrophysiology
2008
Ann N Y Acad Sci. 2008 Mar;1123:224-231.
 
Troponin-positive, CK-MB-negative acute myocardial infarction: clinical, electrocardiographic and angiographic characteristics.
2008
Rafael Beyar, MD, DSc
Authors : Gruberg L, Sudarsky D, Kerner A, Hammerman H, Kapeliovich M
J Invasive Cardiol. 2008 Mar;20(3):125-8. PMID: 18316828 [PubMed - in process]
 
Cell therapy for modification of the myocardial electrophysiological substrate.
2008
Lior Gepstein, MD, PhD
Authors : Yankelson L, Feld Y, Bressler-Stramer T, Itzhaki I, Huber I, Gepstein A, Aronson D, Marom S
Circulation. 2008 Feb 12;117(6):720-31.
 
Heart inefficiency in pulmonary hypertension: a double jeopardy
2008
J Am Coll Cardiol. 2008 Feb 19;51(7):758-9. No abstract available.
 
Ox-LDL induces monocyte-to-macrophage differentiation in vivo: Possible role for the macrophage colony stimulating factor receptor (M-CSF-R).
2008
Michael Aviram, DSc
Authors : Fuhrman B, Partoush A, Volkova N
Atherosclerosis. 2008 Feb;196(2):598-607.
 
Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic:studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro
2008
Michael Aviram, DSc
Authors : Volkova N, Coleman R, Dreher M, Reddy MK, Ferreira D, Rosenblat M.
J Agric Food Chem. 2008 Feb 13;56(3):1148-57.
 
Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: a prospective double-blinded clinical trial.
2008
Andrew P. Levy, MD, PhD, FACC
Authors : Milman U, Blum S, Shapira C, Aronson D, Miller-Lotan R, Anbinder Y, Alshiek J, Bennett L, Kostenko M, Landau M, Keidar S, Levy Y, Khemlin A, Radan A.
Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):341-7.
 
Acute coronary syndrome revisited - markers, interventions and complications.
2008
Acute Card Care. 2008;10(1):3-4.
 
Thrombophilia and adverse pregnancy outcome.
2007
Benjamin Brenner, MD
Authors : Aharon A.
Clin Perinatol. 2007 Dec;34(4):527-41
 
Pharmacogenomics in prevention of diabetic cardiovascular disease: utilization of the haptoglobin genotype in determining benefit from vitamin E.
2007
Expert Rev Cardiovasc Ther. 2007 Nov;5(6):1105-11. Review.
 
Electrophysiological coupling of transplanted cardiomyocytes.
2007
Lior Gepstein, MD, PhD
Authors : Kehat I.
Circ Res. 2007 Aug 31;101(5):433-5
 
Hyperlipidaemia and cardiovascular disease.
2007
Curr Opin Lipidol. 2007 Aug;18(4):473-5.
 
Downregulation of the hemoglobin scavenger receptor in individuals with diabetes and the Hp 2-2 genotype: implications for the response to intraplaque hemorrhage and plaque vulnerability.
2007
Andrew P. Levy, MD, PhD, FACC
Authors : Purushothaman KR, Levy NS, Purushothaman M, Strauss M, Asleh R, Marsh S, Cohen O, Moestrup SK, Moller HJ, Zias EA, Benhayon D, Fuster V, Moreno PR.
Circ Res. 2007 Jul 6;101(1):106-10.
 
Plasma serotonin levels and the platelet serotonin transporter.
2007
Benjamin Brenner, MD
Authors : Harney JT, Ahmed BA, Jeffus BC, Unal R, Mehta JL, Kilic F.
J Neurochem. 2007 Jul;102(1):206-15.
 
Hypothesis--haptoglobin genotype and diabetic nephropathy.
2007
Andrew P. Levy, MD, PhD, FACC
Authors : Nakhoul FM, Miller-Lotan R, Awaad H, Asleh R.
Nat Clin Pract Nephrol. 2007 Jun;3(6):339-44
Consumption of a novel dietary formula of plant sterol esters of canola oil Fatty acids, in a canola oil matrix containing 1,3-diacylglycerol, reduces oxidative stress in atherosclerotic apolipoprotein e-deficient mice.
2007
Michael Aviram, DSc  |   Andrew P. Levy, MD, PhD, FACC
Authors : Fuhrman B, Plat D, Herzog Y.
J Agric Food Chem. 2007 Mar 7;55(5):2028-33.
Haptoglobin genotype modulates the balance of Th1/Th2 cytokines produced by macrophages exposed to free hemoglobin.
2007
Atherosclerosis. 2007 Mar;191(1):48-53.
 
Experience with recombinant-activated factor VII in 30 patients with congenital factor VII deficiency.
2007
Benjamin Brenner, MD
Authors : Wiis J.
Hematology. 2007 Feb;12(1):55-62
Biomarkers, imaging and interventions--going up hill.
2007
Acute Card Care. 2007;9(4):195-6.
 
Haptoglobin genotype determines myocardial infarct size in diabetic mice.
2007
Andrew P. Levy, MD, PhD, FACC
Authors : Blum S, Asaf R, Guetta J, Miller-Lotan R, Asleh R, Kremer R, Levy NS, Berger FG, Aronson D, Fu X, Zhang R, Hazen SL, Levy AP.
J Am Coll Cardiol. 2007 Jan 2;49(1):82-7.
 
Haptoglobin genotype is a determinant of iron, lipid peroxidation, and macrophage accumulation in the atherosclerotic plaque.
2007
Andrew P. Levy, MD, PhD, FACC
Authors : Levy AP, Levy JE, Kalet-Litman S, Miller-Lotan R, Levy NS, Asaf R, Guetta J, Yang C, Purushothaman KR, Fuster V, Moreno PR.
Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):134-40.
 
Markers, lumenology and beyond- focus on acute heart failure and acute coronary conditions.
2007
Acute Card Care. 2007;9(1):4-5
 
Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo.
2006
Andrew P. Levy, MD, PhD, FACC
Authors : Asleh R, Miller-Lotan R, Aviram M, Hayek T, Yulish M, Levy JE, Miller B, Blum S, Milman U, Shapira C, Levy AP.
Circ Res. 2006 Dec 8;99(12):1419-25.
 
Myocardial regeneration strategies using human embryonic stem cell-derived cardiomyocytes.
2006
Lior Gepstein, MD, PhD
Authors : Capi O.
J Control Release. 2006 Nov 28;116(2):211-8.
Application of pharmacogenomics in the prevention of diabetic cardiovascular disease: mechanistic basis and clinical evidence for utilization of the haptoglobin genotype in determining benefit from antioxidant therapy.
2006
Pharmacol Ther. 2006 Nov;112(2):501-12.
Evaluation of ProC Global assay in women with a history of venous thromboembolism on hormonal therapy.
2006
Benjamin Brenner, MD
Authors : Sarig G, Aberbach I, Schliamser L, Blumenfeld Z, Brenner B.
Thromb Haemost. 2006 Nov;96(5):578-83.
 
Interventions to prevent venous thrombosis after air travel, are they necessary? Yes.
2006
Benjamin Brenner, MD
Authors : Brenner B.
J Thromb Haemost. 2006 Nov;4(11):2302-5.
 
The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux.
2006
Michael Aviram, DSc
Authors : Gaidukov L, Rosenblat M, Aviram M, Tawfik DS.
J Lipid Res. 2006 Nov;47(11):2492-502. Epub 2006 Aug 16. PMID: 16914770 [PubMed - indexed for MEDLINE]
 
S-Glutathionylation regulates HDL-associated paraoxonase 1 (PON1) activity.
2006
Michael Aviram, DSc
Authors : Rozenberg O, Aviram M.
Biochem Biophys Res Commun. 2006 Oct 18;351(2):492-498
 
Calcium handling in embryonic stem cell-derived cardiac myocytes: of mice and men.
2006
Lior Gepstein, MD, PhD
Authors : Itzhaki I, Schiller J, Beyar R, Satin J,
Ann N Y Acad Sci. 2006 Oct;1080:207-15.
 
Cardiovascular therapeutic aspects of cell therapy and stem cells.
2006
Ann N Y Acad Sci. 2006 Oct;1080:415-25.
 
Five-year clinical follow up after intracoronary radiation for the prevention of in-stent restenosis.
2006
Rafael Beyar, MD, DSc
Authors : Gruberg L, Caiati R, Aronson D, Suleiman M, Petchersky S, Nikolsky E, Grenadier E, Boulus M, Markiewicz W, Kerner A, Beyar R.
J Invasive Cardiol. 2006 Oct;18(10):494-8.
 
Prevalence of Upper Extremity Deep Venous Thrombosis Diagnosed by Color Doppler Duplex Sonography in Cancer Patients With Central Venous Catheters.
2006
Benjamin Brenner, MD
Authors : Gaitini D, Beck-Razi N, Haim N, Brenner B.
J Ultrasound Med. 2006 Oct;25(10):1297-1303.
 
End-stage renal disease and drug-eluting stents: one small step forward.
2006
Rafael Beyar, MD, DSc
Authors : Gruberg L, Beyar R.
J Invasive Cardiol. 2006 Sep;18(9):409-10.
 
From gene therapy and stem cells to clinical electrophysiology.
2006
Lior Gepstein, MD, PhD
Authors : Yankelson L,Gepstein L.
Pacing Clin Electrophysiol. 2006 Sep;29(9):996-1005.
 
Pomegranate juice shows possible diabetes benefits
2006
Michael Aviram, DSc
Authors : Stephen Daniells and Michael Aviram
Pharmacological prevention of venous thromboembolism before air travel. Is it necessary? Yes.
2006
Benjamin Brenner, MD
Authors : Brenner B.
J Thromb Haemost. 2006 Aug 23; [Epub ahead of print] No abstract available. PMID: 16938123 [PubMed - as supplied by publisher]
Paraoxonase 1 (PON1) is a more potent antioxidant and stimulant of macrophage cholesterol efflux, when present in HDL than in lipoprotein-deficient serum: Relevance to diabetes.
2006
Michael Aviram, DSc
Authors : Rosenblat M, Karry R, Aviram M.
Atherosclerosis. 2006 Jul;187(1):74-81. Epub 2005 Oct 17. PMID: 16229851 [PubMed - in process]
Haptoglobin 1-1 genotype and the risk of life-threatening streptococcus infection: Evolutionary implications.
2006
Andrew P. Levy, MD, PhD, FACC
Authors : Wasserzug O, Blum S, Klement E, Lejbkowicz F, Miller-Lotan R, Levy AP.
Infect. 2006 Jun 29; [Epub ahead of print] No abstract available.
 
Postprandial serum triacylglycerols and oxidative stress in mice after consumption of fish oil, soy oil or olive oil: Possible role for paraoxonase-1 (PON1) triacylglycerol lipase-like activity.
2006
Michael Aviram, DSc
Authors : Fuhrman B, Volkova N, Aviram M.
Nutrition. 2006 Jun 29; [Epub ahead of print] PMID: 16814984 [PubMed - as supplied by publisher]
 
Lysophosphatidylcholine (LPC) attenuates macrophage-mediated oxidation of LDL.
2006
Michael Aviram, DSc
Authors : Rosenblat M, Oren R, Aviram M.
Biochem Biophys Res Commun. 2006 Jun 16;344(4):1271-7.
A randomized study of thromboprophylaxis in women with unexplained consecutive recurrent miscarriages.
2006
Benjamin Brenner, MD
Authors : Dolitzky M, Inbal A, Segal Y, Weiss A, Brenner B, Carp H.
Fertil Steril. 2006 Jun 9; [Epub ahead of print] PMID: 16769056 [PubMed - as supplied by publisher]
Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus.
2006
Andrew P. Levy, MD, PhD, FACC
Authors : Miller-Lotan R, Miller B, Nakhoul F, Aronson D, Asaf R, Levy AP.
Diabetes Metab Res Rev. 2006 Jun 2; [Epub ahead of print] PMID: 16742000 [PubMed - as supplied by publisher]
Preprocedural C-reactive protein levels predict myocardial necrosis after successful coronary stenting in patients with stable angina.
2006
Rafael Beyar, MD, DSc
Authors : Goldberg A, Gruberg L, Roguin A, Petcherski S, Rimer D, Markiewicz W, Beyar R, Aronson D.
Am Heart J. 2006 Jun;151(6):1265-70. PMID: 16781234 [PubMed - in process]
 
Neovascularization in human atherosclerosis.
2006
Andrew P. Levy, MD, PhD, FACC
Authors : Moreno PR, Purushothaman KR, Sirol M, Levy AP, Fuster V.
Circulation. 2006 May 9;113(18):2245-52. Review. No abstract available. PMID: 16684874 [PubMed - indexed for MEDLINE]
Duplex Ultrasound Verified by Angiography in Patients with Severe Primary and Restenosis of Internal Carotid Artery.
2006
Rafael Beyar, MD, DSc
Authors : Telman G, Kouperberg E, Sprecher E, Gruberg L, Beyar R, Hoffman A, Yarnitsky D.
Ann Vasc Surg. 2006 Apr 27; [Epub ahead of print] PMID: 16642286 [PubMed - as supplied by publisher]
Hyponatremia and long-term mortality in survivors of acute ST-elevation myocardial infarction.
2006
Rafael Beyar, MD, DSc
Authors : Goldberg A, Hammerman H, Petcherski S, Nassar M, Zdorovyak A, Yalonetsky S, Kapeliovich M, Agmon Y, Beyar R, Markiewicz W, Aronson D.
Arch Intern Med. 2006 Apr 10;166(7):781-6. PMID: 16606816 [PubMed - indexed for MEDLINE]
Acute cardiac care: apocalypse now!
2006
Rafael Beyar, MD, DSc
Authors : Beyar R, Filippatos G, Gheorghiade M, Tamai H, Galvani M, Hasin Y, Keren G, Leon MB.
Acute Card Care. 2006 Apr;8(1):4-6. No abstract available. PMID: 16720420 [PubMed - in process]
Carotid artery stenting in surgical high-risk patients.
2006
Rafael Beyar, MD, DSc
Authors : Halabi M, Gruberg L, Pitchersky S, Kouperberg E, Nikolsky E, Hoffman A, Beyar R.
Catheter Cardiovasc Interv. 2006 Apr;67(4):513-8. PMID: 16534816 [PubMed - in process]
Multicenter evaluation of a self-expanding carotid stent system with distal protection in the treatment of carotid stenosis.
2006
Rafael Beyar, MD, DSc
Authors : Hill MD, Morrish W, Soulez G, Nevelsteen A, Maleux G, Rogers C, Hauptmann KE, Bonafe A, Beyar R, Gruberg L, Schofer J; MAVErlC International Investigators.
AJNR Am J Neuroradiol. 2006 Apr;27(4):759-65. PMID: 16611760 [PubMed - in process]
The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux.
2006
Michael Aviram, DSc
Authors : Rosenblat M, Gaidukov L, Khersonsky O, Vaya J, Oren R, Tawfik DS, Aviram M.
J Biol Chem. 2006 Mar 17;281(11):7657-65. Epub 2006 Jan 10. PMID: 16407304 [PubMed - indexed for MEDLINE]
Pomegranate byproduct administration to apolipoprotein e-deficient mice attenuates atherosclerosis development as a result of decreased macrophage oxidative stress
2006
Michael Aviram, DSc
Authors : Rosenblat M, Volkova N, Coleman R, Aviram M.
J Agric Food Chem. 2006 Mar 8;54(5):1928-35. PMID: 16506855 [PubMed - indexed for MEDLINE]
Early inflammation and risk of long-term development of heart failure and mortality in survivors of acute myocardial infarction predictive role of C-reactive protein.
2006
Rafael Beyar, MD, DSc
Authors : Suleiman M, Khatib R, Agmon Y, Mahamid R, Boulos M, Kapeliovich M, Levy Y, Beyar R, Markiewicz W, Hammerman H, Aronson D.
J Am Coll Cardiol. 2006 Mar 7;47(5):962-8. PMID: 16516078 [PubMed - indexed for MEDLINE]
Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin.
2006
Benjamin Brenner, MD
Authors : Nasser NJ, Sarig G, Brenner B, Nevo E, Goldshmidt O, Zcharia E, Li JP, Vlodavsky I.
J Thromb Haemost. 2006 Mar;4(3):560-5. PMID: 16460439 [PubMed - indexed for MEDLINE]
Regenerating the heart using human embryonic stem cells--from cell to bedside.
2006
Lior Gepstein, MD, PhD
Authors : Caspi O, Gepstein L.
Isr Med Assoc J. 2006 Mar;8(3):208-14. Review. PMID: 16599061 [PubMed - indexed for MEDLINE]
Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction.
2006
Ofer Binah, PhD
Authors : Dolnikov K, Shilkrut M, Zeevi-Levin N, Gerecht-Nir S, Amit M, Danon A, Itskovitz-Eldor J, Binah O.
Stem Cells. 2006 Feb;24(2):236-45.
Glycoprotein IIb/IIIa inhibitors during rescue percutaneous coronary intervention in acute myocardial infarction.
2006
Rafael Beyar, MD, DSc
Authors : Gruberg L, Suleiman M, Kapeliovich M, Hammerman H, Grenadier E, Boulus M, Amikam S, Markiewicz W, Beyar R.
J Invasive Cardiol. 2006 Feb;18(2):59-62. PMID: 16446517 [PubMed - indexed for MEDLINE]
Remote-control percutaneous coronary interventions: concept, validation, and first-in-humans pilot clinical trial.
2006
Rafael Beyar, MD, DSc
Authors : Beyar R, Gruberg L, Deleanu D, Roguin A, Almagor Y, Cohen S, Kumar G, Wenderow T.
J Am Coll Cardiol. 2006 Jan 17;47(2):296-300. Epub 2006 Jan 4. PMID: 16412850 [PubMed - indexed for MEDLINE]
16-MDCT coronary angiography versus invasive coronary angiography in acute chest pain syndrome: a blinded prospective study.
2006
Rafael Beyar, MD, DSc
Authors : Ghersin E, Litmanovich D, Dragu R, Rispler S, Lessick J, Ofer A, Brook OR, Gruberg L, Beyar R, Engel A.
AJR Am J Roentgenol. 2006 Jan;186(1):177-84. PMID: 16357399 [PubMed - indexed for MEDLINE]
A mouse model for human atherosclerosis: long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice.
2006
Michael Aviram, DSc
Authors : Coleman R, Hayek T, Keidar S, Aviram M.
Acta Histochem. 2006;108(6):415-24. Epub 2006 Sep 26. Review. PMID: 17007910 [PubMed - indexed for MEDLINE]
 
Acute Cardiac Care: the lifting of the veil.
2006
Rafael Beyar, MD, DSc
Authors : Beyar R, Filippatos G.
Acute Card Care. 2006;8(3):131-2.
 
Contrast enhanced multi-detector computed tomography coronary angiography versus conventional invasive quantitative coronary angiography in acute coronary syndrome patients-correlation and bias.
2006
Rafael Beyar, MD, DSc
Authors : Dragu R, Rispler S, Ghersin E, Gruberg L, Lessick J, Litmanovich D, Aronson D, Hammerman H, Ofer A, Engel A, Beyar R.
Acute Card Care. 2006;8(2):99-104. PMID: 16885074 [PubMed - in process]
 
Effect of a Mediterranean meal on postprandial carotenoids, paraoxonase activity and C-reactive protein levels.
2006
Michael Aviram, DSc
Authors : Blum S, Aviram M, Ben-Amotz A, Levy Y.
Ann Nutr Metab. 2006;50(1):20-4. Epub 2005 Nov 4. PMID: 16276071 [PubMed - indexed for MEDLINE]
Exogenous N-linoleoyl tyrosine marker as a tool for the characterization of cellular oxidative stress in macrophages.
2006
Michael Aviram, DSc
Authors : Szuchman A, Aviram M, Soliman K, Tamir S, Vaya J.
Free Radic Res. 2006 Jan;40(1):41-52. PMID: 16298758 [PubMed - indexed for MEDLINE]
Haptoglobin phenotypes, which one is better and when?
2006
Andrew P. Levy, MD, PhD, FACC
Authors : Zvi B, Levy AP.
Clin Lab. 2006;52(1-2):29-35. PMID: 16506361 [PubMed - in process]
The eccentric lumenology.
2006
Rafael Beyar, MD, DSc
Authors : Nair P, Gruberg L, Beyar R.
Acute Card Care. 2006;8(2):87-94.
 
Thrombophilia and pregnancy complications.
2006
Benjamin Brenner, MD
Authors : Brenner B.
Pathophysiol Haemost Thromb. 2006;35(1-2):28-35.
 
Pomegranate juice sugar fraction reduces macrophage oxidative state, whereas white grape juice sugar fraction increases it.
2005
Michael Aviram, DSc
Authors : Rozenberg O, Howell A, Aviram M.
Atherosclerosis. 2005 Dec 2; [Epub ahead of print] PMID: 16332370 [PubMed - as supplied by publisher]
Endoluminal hydrogel films made of alginate and polyethylene glycol: physical characteristics and drug-eluting properties.
2005
Rafael Beyar, MD, DSc
Authors : Livnat M, Beyar R, Seliktar D.
J Biomed Mater Res A. 2005 Dec 1;75(3):710-22. PMID: 16100722 [PubMed - indexed for MEDLINE]
Stem cells as biological heart pacemakers.
2005
Lior Gepstein, MD, PhD
Authors : Gepstein L.
Expert Opin Biol Ther. 2005 Dec;5(12):1531-7. Review. PMID: 16318417 [PubMed - indexed for MEDLINE]
Coronary perforation 2006 - watch for the wire.
2005
Rafael Beyar, MD, DSc
Authors : Roguin A, Beyar R.
J Invasive Cardiol. 2005 Nov;17(11):606-8. No abstract available. PMID: 16264207 [PubMed - indexed for MEDLINE]
Hemostatic balance on the surface of leukemic cells: the role of tissue factor and urokinase plasminogen activator receptor.
2005
Benjamin Brenner, MD
Authors : Nadir Y, Katz T, Sarig G, Hoffman R, Oliven A, Rowe JM, Brenner B.
Haematologica. 2005 Nov;90(11):1549-56. PMID: 16266903 [PubMed - in process]
Macrophage foam-cell formation in streptozotocin-induced diabetic mice: stimulatory effect of glucose.
2005
Michael Aviram, DSc
Authors : Hayek T, Hussein K, Aviram M, Coleman R, Keidar S, Pavoltzky E, Kaplan M.
Atherosclerosis. 2005 Nov;183(1):25-33. Epub 2005 Apr 1. PMID: 16216589 [PubMed - indexed for MEDLINE]
Modulation of systemic hemostatic parameters by enoxaparin during gestation in women with thrombophilia and pregnancy loss.
2005
Benjamin Brenner, MD
Authors : Sarig G, Blumenfeld Z, Leiba R, Lanir N, Brenner B.
Thromb Haemost. 2005 Nov;94(5):980-5. PMID: 16363240 [PubMed - indexed for MEDLINE]
Hydrogen peroxide predisposes neonatal rat ventricular myocytes to Fas-mediated apoptosis.
2005
Ofer Binah, PhD
Authors : Yaniv G, Shilkrut M, Larisch S, Binah O.
Biochem Biophys Res Commun. 2005 Oct 28;336(3):740-6. PMID: 16157298 [PubMed - indexed for MEDLINE]
Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages.
2005
Michael Aviram, DSc
Authors : Rosenblat M, Hayek T, Aviram M.
Atherosclerosis. 2005 Oct 11; [Epub ahead of print] PMID: 16226266 [PubMed - as supplied by publisher]
The 1,4,5-inositol trisphosphate pathway is a key component in Fas-mediated hypertrophy in neonatal rat ventricular myocytes.
2005
Ofer Binah, PhD
Authors : Barac YD, Zeevi-Levin N, Yaniv G, Reiter I, Milman F, Shilkrut M, Coleman R, Abassi Z, Binah O.
Cardiovasc Res. 2005 Oct 1;68(1):75-86. PMID: 16005448 [PubMed - indexed for MEDLINE]
Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages.
2005
Michael Aviram, DSc
Authors : Fuhrman B, Volkova N, Aviram M.
J Nutr Biochem. 2005 Sep;16(9):570-6. PMID: 16115546 [PubMed - indexed for MEDLINE]
Increased blood vessel density provides the mole rat physiological tolerance to its hypoxic subterranean habitat.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Avivi A, Shams I, Joel A, Lache O, Levy AP, Nevo E.
FASEB J. 2005 Aug;19(10):1314-6. Epub 2005 Jun 13. PMID: 16000366 [PubMed - indexed for MEDLINE]
Paraoxonases (PONs) 1, 2, and 3 are expressed in human and mouse gastrointestinal tract and in Caco-2 cell line: selective secretion of PON1 and PON2.
2005
Michael Aviram, DSc
Authors : Shamir R, Hartman C, Karry R, Pavlotzky E, Eliakim R, Lachter J, Suissa A, Aviram M.
Free Radic Biol Med. 2005 Aug 1;39(3):336-44. Epub 2005 Apr 6. PMID: 15993332 [PubMed - indexed for MEDLINE]
Paraoxonases and cardiovascular diseases: pharmacological and nutritional influences.
2005
Michael Aviram, DSc
Authors : Aviram M, Rosenblat M.
Curr Opin Lipidol. 2005 Aug;16(4):393-9. Review. PMID: 15990587 [PubMed - indexed for MEDLINE]
Effect of obesity on the relationship between plasma C-reactive protein and coronary artery stenosis in patients with stable angina
2005
Rafael Beyar, MD, DSc
Authors : Aronson D, Goldberg A, Roguin A, Petcherski S, Rimer D, Gruberg L, Avizohar O, Levy Y, Markiewicz W, Beyar R.
Atherosclerosis. 2006 Mar;185(1):137-42. Epub 2005 Jul 15. PMID: 16024024 [PubMed - indexed for MEDLINE]
Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Miller-Lotan R, Herskowitz Y, Kalet-Litman S, Nakhoul F, Aronson D, Zoabi R, Asaf R, Ben-Izhak O, Sabo E, Lim SK, Baumann H, Berger FG, Levy AP.
Diabetes Metab Res Rev. 2005 Jul-Aug;21(4):332-7. PMID: 15852445 [PubMed - indexed for MEDLINE]
Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants.
2005
Michael Aviram, DSc
Authors : Azadzoi KM, Schulman RN, Aviram M, Siroky MB.
J Urol. 2005 Jul;174(1):386-93. PMID: 15947695 [PubMed - indexed for MEDLINE]
Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice
2005
Michael Aviram, DSc
Authors : Rozenberg O, Shih DM, Aviram M.
Atherosclerosis. 2005 Jul;181(1):9-18. PMID: 15939049 [PubMed - indexed for MEDLINE]
Differentiation pathways in human embryonic stem cell-derived cardiomyocytes.
2005
Lior Gepstein, MD, PhD
Authors : Lev S, Kehat I, Gepstein L.
Ann N Y Acad Sci. 2005 Jun;1047:50-65. Review. PMID: 16093484 [PubMed - indexed for MEDLINE]
From organ to molecules: steps and consequences.
2005
Rafael Beyar, MD, DSc
Authors : Beyar R.
Ann N Y Acad Sci. 2005 Jun;1047:1-12. Review. PMID: 16093480 [PubMed - indexed for MEDLINE]
The impact of GP IIb/IIIa inhibitors during primary percutaneous coronary intervention in acute myocardial infarction patients.
2005
Rafael Beyar, MD, DSc
Authors : Lavi S, Gruberg L, Kapeliovich M, Hammerman H, Boulos M, Grenadier E, Aronson D, Markiewicz W, Beyar R.
J Invasive Cardiol. 2005 Jun;17(6):296-9. PMID: 16003002 [PubMed - indexed for MEDLINE]
Paraoxonase 1 (PON1) is present in postprandial chylomicrons.
2005
Michael Aviram, DSc
Authors : Fuhrman B, Volkova N, Aviram M.
Atherosclerosis. 2005 May;180(1):55-61. Epub 2005 Jan 15. PMID: 15823275 [PubMed - indexed for MEDLINE]
Usefulness of electroanatomical mapping to differentiate between right ventricular outflow tract tachycardia and arrhythmogenic right ventricular dysplasia.
2005
Lior Gepstein, MD, PhD
Authors : Boulos M, Lashevsky I, Gepstein L.
Am J Cardiol. 2005 Apr 15;95(8):935-40. PMID: 15820158 [PubMed - indexed for MEDLINE
Gap junctional remodeling by hypoxia in cultured neonatal rat ventricular myocytes.
2005
Ofer Binah, PhD
Authors : Zeevi-Levin N, Barac YD, Reisner Y, Reiter I, Yaniv G, Meiry G, Abassi Z, Kostin S, Schaper J, Rosen MR, Resnick N, Binah O.
Cardiovasc Res. 2005 Apr 1;66(1):64-73. PMID: 15769449 [PubMed - indexed for MEDLINE]
Grape powder polyphenols attenuate atherosclerosis development in apolipoprotein E deficient (E0) mice and reduce macrophage atherogenicity.
2005
Michael Aviram, DSc
Authors : Fuhrman B, Volkova N, Coleman R, Aviram M.
J Nutr. 2005 Apr;135(4):722-8. PMID: 15795424 [PubMed - indexed for MEDLINE]
Prospective motion correction of X-ray images for coronary interventions.
2005
Rafael Beyar, MD, DSc
Authors : Shechter G, Shechter B, Resar JR, Beyar R.
IEEE Trans Med Imaging. 2005 Apr;24(4):441-50. PMID: 15822802 [PubMed - indexed for MEDLINE]
Haptoglobin genotype- and diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Asleh R, Guetta J, Kalet-Litman S, Miller-Lotan R, Levy AP.
Circ Res. 2005 Mar 4;96(4):435-41. Epub 2005 Jan 20. PMID: 15662028 [PubMed - indexed for MEDLINE]
Angiogenesis--an update.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Roguin A, Levy AP.
Pediatr Endocrinol Rev. 2005 Mar;2(3):391-8. Review. PMID: 16429116 [PubMed - indexed for MEDLINE]
Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine.
2005
Michael Aviram, DSc
Authors : Rosenblat M, Vaya J, Shih D, Aviram M.
Atherosclerosis. 2005 Mar;179(1):69-77. Epub 2004 Dec 29. PMID: 15721011 [PubMed - indexed for MEDLINE]
Impact of body mass index on the outcome of patients with multivessel disease randomized to either coronary artery bypass grafting or stenting in the ARTS trial: The obesity paradox II?
2005
Rafael Beyar, MD, DSc
Authors : Gruberg L, Mercado N, Milo S, Boersma E, Disco C, van Es GA, Lemos PA, Ben Tzvi M, Wijns W, Unger F, Beyar R, Serruys PW; Arterial Revascularization Therapies Study Investigators.
Am J Cardiol. 2005 Feb 15;95(4):439-44. PMID: 15695125 [PubMed - indexed for MEDLINE]
Haptoglobin phenotype, sleep-disordered breathing, and the prevalence of cardiovascular disease: the Sleep Heart Health Study.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Levy AP, Zhang L, Miller-Lotan R, Redline S, O'Connor GT, Quan SF, Resnick HE.
Sleep. 2005 Feb 1;28(2):207-13. PMID: 16171245 [PubMed - indexed for MEDLINE]
New horizons for VEGF. Is there a role for nuclear localization?
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Lejbkowicz F, Goldberg-Cohen I, Levy AP.
Acta Histochem. 2005;106(6):405-11. Epub 2005 Jan 13. PMID: 15707649 [PubMed - indexed for MEDLINE]
Cerebral embolic protection devices and percutaneous carotid artery stenting.
2005
Rafael Beyar, MD, DSc
Authors : Gruberg L, Beyar R.
Int J Cardiovasc Intervent. 2005;7(3):117-21. Review. No abstract available. PMID: 16243731 [PubMed - indexed for MEDLINE]
 
Dietary antioxidants and paraoxonases against LDL oxidation and atherosclerosis development.
2005
Michael Aviram, DSc
Authors : Aviram M, Kaplan M, Rosenblat M, Fuhrman B.
Handb Exp Pharmacol. 2005;(170):263-300. Review. PMID: 16596803 [PubMed - indexed for MEDLINE]
Functional properties of human embryonic stem cell-derived cardiomyocytes.
2005
Ofer Binah, PhD
Authors : Dolnikov K, Shilkrut M, Zeevi-Levin N, Danon A, Gerecht-Nir S, Itskovitz-Eldor J, Binah O.
Ann N Y Acad Sci ;1047:66-75.
 
Haptoglobin genotypeand diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Asleh R, Guetta J, Kalet-Litman S, Miller-Lotan R, Levy AP.
Circ Res ;96:435-441.
 
Haptoglobin polymorphism predicts 30-day mortality and heart failure in patients with diabetes and acute myocardial infarction.
2005
Andrew P. Levy, MD, PhD, FACC
Authors : Suleiman M, Aronson D, Asleh R, Kapeliovich MP, Roguin A, Meisel SR, Shochat M, Sulieman A, Reisner SA, Markiewicz W, Hammerman H, Lotan R, Levy NS, Levy AP.
Diabetes ; 54:2802-2806.
 
In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease.
2005
Vasc Health Risk Manag. 2005;1(1):19-28. PMID: 17319095 [PubMed - in process]
Placental TFPI is decreased in gestational vascular complications and can be restored by maternal enoxaparin treatment.
2005
Benjamin Brenner, MD
Authors : Aharon A, Lanir N, Drugan A, Brenner B.
J Thromb Haemost;3:10-2355.
 
Clinical management of thrombophilia-related placental vascular complications.
2004
Blood ;103:4003-4009.
 
Coagulation, inflammation, and pregnancy complications.
2004
Benjamin Brenner, MD
Authors : Sarig G, Brenner B.
Lancet ;363:96-97.
 
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells.
2004
Lior Gepstein, MD, PhD
Authors : Kehat I, Khimovich L, Caspi O, Gepstein A, Shofti R, Arbel G, Huber I, Satin J, Itskovitz-Eldor J, Gepstein L.
Nat Biotechnol ;22:1282-1289.
 
Novel approaches to reduce restenosis
2004
Rafael Beyar, MD, DSc
Authors : Beyar R.
Ann N Y Acad Sci ; 1015:367-378.
 
Paraoxonases 1, 2, and 3, oxidative stress,and macrophage foam cell formation during atherosclerosis development.
2004
Michael Aviram, DSc
Authors : Aviram M, Rosenblat M.
Free Radic Biol Med ;37:1304-1316.
 
Large a-v fistula: pathophysiologic consequences and therapeutic perspectives
2003
Aaron Hoffman, MD
Authors : Abassi, Z., Winaver, J., Hoffman, A.
Curr Vasc Pharmacol 1, 347-354.
 
Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation.
2003
Michael Aviram, DSc
Authors : Rozenberg O, Shih DM, Aviram M.
Arterioscler Thromb Vasc Biol ;23:461-467.
 
Effects of endothelin receptors ETA and ETB blockade on renal haemodynamics in normal rats and in rats with experimental congestive heart failure
2002
Aaron Hoffman, MD
Authors : Abassi, Z., Francis, B., Wessale, J., Ovcharenko, E., Winaver, J., Hoffman, A.
Clin Sci 103, 245S-248S.
 
Electrophysiological modulation of cardiomyocytic tissue by transfected fibroblasts expressing potassium channels: a novel strategy to manipulate excitability.
2002
Lior Gepstein, MD, PhD
Authors : Feld Y, Melamed-Frank M, Kehat I, Tal D, Marom S, Gepstein L.
Circulation ;105:522-529.
 
Anti-atherogenicity of nutritional antioxidants
2001
Michael Aviram, DSc
Authors : Fuhrman B, Aviram M.
IDrugs. 2001 Jan;4(1):82-92. PMID: 16034706 [PubMed]
Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes.
2001
Lior Gepstein, MD, PhD
Authors : Kehat I, Kenyagin-Karsenti D, Snir M, Segev H, Amit M, Gepstein A, Livne E, Binah O, Itskovitz-Eldor J, Gepstein L.
J Clin Invest ;108:407-414.
 
Mechanisms of big endothelin-1-induced diuresis and natriuresis: role of ETB receptors
2000
Aaron Hoffman, MD
Authors : Hoffman, A., Abassi, Z. A., Brodsky, S., Ramadan, R., Winaver, J.
Hypertension 35, 732-739.
 
Haptoglobin phenotype and vascular complications in patients with diabetes.
2000
Andrew P. Levy, MD, PhD, FACC
Authors : Levy AP, Roguin A, Hochberg I, Herer P, Marsh S, Nakhoul FM, Skorecki K.
N Engl J Med ;343:969-970.
 
Effect of low altitude at the Dead Sea on exercise capacity and cardiopulmonary response to exercise in cystic fibrosis patients with moderate to severe lung disease.
1900
Michael Aviram, DSc
Authors : Falk B, Nini A, Zigel L, Yahav Y, Aviram M, Rivlin J, Bentur L, Avital A, Dotan R, Blau H.
Pediatr Pulmonol. 2006 Mar;41(3):234-41. PMID: 16429430 [PubMed - in process]
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Translational Genetics center

The inauguration of the newly established Center for Translational Genetics at the Rappaport Institute.

2008 David Shoham Prizes

The David Shoham Prize award ceremony took place on June 11th, at the Rappaport Institute.

The Nobel Prize in Chemistry 2004

Professors Avram Hershko and Aaron Ciechanover - winners of the 2004 Nobel Prize in Chemistry.
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